Sökning: "cerebral lactate"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden cerebral lactate.

  1. 1. Astrocyte metabolism following focal cerebral ischemia

    Författare :Anna E Thoren; Göteborgs universitet; []
    Nyckelord :Astrocyte; metabolism; focal cerebral ischemia; reperfusion; infarct; [1-14C]acetate; [U-14C]glucose; glutamine; glutamate; ATP; ADP; lactate; MCT4; immunogold cytochemistry;

    Sammanfattning : Stroke is one of the leading causes of disability and death. Most often, stroke results from blockage of an artery in the brain leading to tissue infarction within the perfusion territory of the affected vessel. LÄS MER

  3. 2. Bedside monitoring of cerebral energy metabolism using intracerebral microdialysis during neuro intensive care

    Författare :Nils Ståhl; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; Neurologi; neuropsychology; Neurology; glycerol.; glutamate; pyruvate; lactate; glucose; hyperglycaemia; intensive care; brain injury; Human; cerebral microdialysis; neurophysiology;

    Sammanfattning : In clinical situations with raised intracranial pressure (ICP) and impending insufficient cerebral blood flow (ischaemia), bedside information about energy metabolism in the brain would be helpful. Microdialysis is a technique that makes it possible to monitor the interstitial concentrations of various compounds in an organ. LÄS MER

  4. 3. ICU prognostication: Time to re-evaluate? Register-based studies on improving prognostication for patients admitted to the intensive care unit (ICU)

    Författare :Peder Andersson; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intensive Care; Critical Care; Mortality; Cerebral Performance Category; Cardiac arrest; Out-of-hospital cardiac arrest; Sepsis; Lactate; Troponin; Neuron-specific enolase; Neurofilament light; Age; Elderly; Prognostication; Prediction; Scoring system; Neural net; Artificial neural network; Deep learning; Artificial intelligence;

    Sammanfattning : Background: ICU prognostication is difficult because of patients’ prior comorbidities and their varied reasons for admission. The model used for ICU prognostication in Sweden is the Simplified Acute Physiology Score 3 (SAPS 3), which uses information gathered within one hour of ICU admission to predict 30-day mortality. LÄS MER

  5. 4. Glutamate Turnover and Energy Metabolism in Brain Injury : Clinical and Experimental Studies

    Författare :Carolina Samuelsson; Elisabeth Ronne-Engström; Lars Hillered; Eva Kumlien; Carl-Henrik Nordström; Uppsala universitet; []
    Nyckelord :Neurosciences; glutamate; glutamine; lactate; pyruvate; microdialysis; GLT-1; energy metabolism; intracranial pressure; cerebral perfusion pressure; subarachnoid hemorrhage; ischemia; epilepsy; Neurovetenskap;

    Sammanfattning : During brain activity neurons release the major excitatory transmitter glutamate, which is taken up by astrocytes and converted to glutamine. Glutamine returns to neurons for re-conversion to glutamate. This glutamate-glutamine cycle is energy demanding. LÄS MER

  7. 5. Cerebral ischemia studied with positron emission tomography and microdialysis

    Författare :Peter Frykholm; Peter Kirkpatrick; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Cerebral ischemia; penumbra; positron emission tomography; microdialysis; middle cerebral artery occlusion; Neurovetenskap; Neurology; Neurologi; Neurosurgery; neurokirurgi;

    Sammanfattning : Stroke is the third leading cause of morbidity and mortality in the industrialized world. Subarachnoid hemorrhage (SAH), the least common form of stroke, is one of the most demanding diseases treated in neurointensive care units. Cerebral ischemia may develop rapidly, and has a major influence on outcome. LÄS MER