Sökning: "cell proliferation"
Visar resultat 21 - 25 av 1631 avhandlingar innehållade orden cell proliferation.
21. Active cellular forces in variable mechanical microenvironments
Sammanfattning : Our bodies are immensely complex structures, with various systems, organs, and processes that are not only biochemically driven, but strongly dependent on physical mechanics. At the heart of all these processes are cells, which must generate forces to adhere, spread, differentiate, grow, and move. LÄS MER
22. Helicobacter spp. interactions with mucins: adhesion and mucin regulation of pathogen proliferation and gene expression
Sammanfattning : Helicobacter pylori colonizes the gastric mucosa of approximately half of the world’s population and is a risk factor for gastritis, peptic ulcers and gastric cancer. H. pylori is surrounded by, and adheres to, the heavily glycosylated mucins that build up the mucus layer. The carbohydrate structures on the mucins that act as ligands for H. LÄS MER
23. Genetic and Epigenetic Profiling of Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia
Sammanfattning : Mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) both belong to the group of mature B-cell malignancies. However, MCL is typically clinically aggressive while the clinical course of CLL varies. LÄS MER
24. The role of Smad7 and TRAF6 in Prostate Cancer Cell Invasion, Migration and Survival
Sammanfattning : Transforming growth factor (TGF) β is a tumor suppressor during early tumor development, by inhibiting proliferation and inducing apoptosis. At later stages of cancer, it becomes a tumor promoter, and promotes tumor cell migration and invasion. TGFβ signals via its type II and type I receptors to several downstream signaling pathways. LÄS MER
25. Notch signalling in carcinogenesis : With special emphasis on T-cell lymphoma and colorectal cancer
Sammanfattning : The Notch signalling pathway is an evolutionary conserved pathway, named after the Notch receptors, Notch1-4 in mammals, which upon cell-cell contact and ligand binding releases the intracellular domain (NICD). NICD translocates into the nucleus where it binds the transcriptional repressor RBP-Jk, which together with co-activators belonging to the Mastermind-like family of proteins form a transcriptional activation complex. LÄS MER