Sökning: "carbohydrate synthesis"

Visar resultat 21 - 25 av 95 avhandlingar innehållade orden carbohydrate synthesis.

  1. 21. Structure, dynamics and interactions of biomolecules : Investigations by NMR spectroscopy and computational methods

    Författare :Jens Landström; Göran Widmalm; Pedro Nieto; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; MD simulation; carbohydrate synthesis; protein-ligand interaction; glycosyltransferase; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : In this thesis, the structure, dynamics and interactions of proteins and carbohydrates are investigated using mainly NMR spectroscopy and computer simulations. Oligosaccharides representing a Salmonella O-antigen have been synthesized and their dynamic behavior and interaction with the bacteriophage P22 tail-spike protein have been studied by NMR spectroscopy, MD and docking simulations. LÄS MER

  3. 22. Macrocyclic Carbohydrate/Amino Acid Hybrid Molecules - Synthesis and Evaluation as Artificial Receptors

    Författare :Johan Billing; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 3-dipolar cycloaddition; 3-triazoles; 2; 1; molecular recognition; artificial receptors; sugar amino acids; cyclic peptides; macrocycles; Organic chemistry; Organisk kemi;

    Sammanfattning : Methods were developed for the synthesis of three different types of macrocyclic carbohydrate/amino acid hybrid molecules. In the synthesis of the first type of macrocycles, a glucosamine derivative was oxidized at C6 and the obtained sugar amino acid was coupled to tripeptides. LÄS MER

  4. 23. The sweet side of molecular structure : NMR spectroscopic studies of glycans and their interactions with proteins

    Författare :Christoffer Hamark; Göran Widmalm; Mario Schubert; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioorganic chemistry; glycans; ligand-based NMR; molecular simulations; protein-carbohydrate interactions; lectins; carbohydrate conformations; 77Se NMR; structure-reactivity relationships; super-armed donors; organisk kemi; Organic Chemistry;

    Sammanfattning : In this thesis, within the topic of bioorganic chemistry, the molecular structure of carbohydrates has been studied. Carbohydrates, or glycans, are ubiquitous biomolecules exhibiting a wide range of biological roles. LÄS MER

  5. 24. Chemoenzymatic synthesis of anionic alkyl glycosides

    Författare :NGOC NGO; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Alkyl glycosides; laccase; TEMPO; oxidation; cyclodextrin glucanotransferases;

    Sammanfattning : Growing concerns for environmental issues and product safety for users have shifted research interests towards the use of renewable resources and climate-neutral processes. The enzymatic approach having high selectivity under mild reaction conditions is promising, and the nature-originating products are well accepted. LÄS MER

  7. 25. Synthesis of some low molecular weight carbohydrate phosphate esters of biological significance

    Författare :Ingvar Lindh; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER