Sökning: "bisphosphonate"
Visar resultat 6 - 10 av 33 avhandlingar innehållade ordet bisphosphonate.
6. Bone Regeneration with Cell-free Injectable Scaffolds
Sammanfattning : Bone is a remarkable multifunctional tissue with the ability to regenerate and remodel without generating any scar tissue. However, bone loss due to injury or diseases can be a great challenge and affect the patient significantly. Autologous bone grafting is commonly used throughout the world. LÄS MER
7. Improved titanium and steel implants : Studies on bisphosphonate, strontium and surface treatments
Sammanfattning : Purpose: The general aim of this thesis was to increase the understanding of biomaterial surface modifications and local delivery of osteoporosis drugs for bone integration. We therefore (i) characterised and investigated model surface coatings for controlled drug delivery in a rat tibia screw model (ii) elucidated the effect of surface treatment for activation of complement system in vitro. LÄS MER
8. Surface bound bisphosphonate for implant fixation in bone
Sammanfattning : During the surgical preparation of bone, prior to insertion of an implant, bone will be traumatized which leads to local resorption. Consequently, early implant fixation might be reduced. Impaired early fixation, as evidenced by radiostereometry, has been associated with increased risk of late loosening. LÄS MER
9. Developmental disturbances of cementum induced by 1-hydroxyethylidene-1, 1-bisphosphonate (HEBP) : experimental studies on rats
Sammanfattning : By studying the mechanism(s) behind experimentally induced developmental disturbances of a tissue, it may be possible to gain information about its normal development. Cementum seems to be the least understood of the dental tissues, and there are very few studies in which its development has been experimentally altered. LÄS MER
10. Bisphosphonate treatment of children and adolescents with osteogenesis imperfecta : effects on clinical symptoms and bone turnover
Sammanfattning : Background: Osteogenesis imperfecta (OI) is a group of genetic diseases with a wide spectrum of severity, ranging from very mild bone fragility to lethal forms. Without treatment the more severe forms have multiple fractures leading to progressive bone deformities with extreme shortness, frequent skeletal pain and immobilisation. LÄS MER