Sökning: "biological treatment planning"

Visar resultat 1 - 5 av 39 avhandlingar innehållade orden biological treatment planning.

  1. 1. Radiation therapy of upper gastrointestinal cancers with scanned proton beams : A treatment planning study

    Författare :Gracinda Mondlane; Albert Siegbahn; Michael Gubanski; Iuliana Toma-Dasu; Crister Ceberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Treatment planning; gastric cancer; liver metastases; photon beam therapy; proton beam therapy; dosimetric comparison; normal tissue complication probability; risk of radiation-induced secondary cancer; patient selection; Medical Radiation Physics; medicinsk strålningsfysik;

    Sammanfattning : Proton beam therapy (PBT), using scanned beams, is an emerging modality used for the treatment of cancer. The clinical advantages of PBT, compared to commonly used photon beam therapy, have been demonstrated in different studies. LÄS MER

  3. 2. Development and application of composite energy deposition kernels for photon therapy planning

    Författare :Anders Eklöf; Simo Hyödynmaa; Stockholms universitet; []
    Nyckelord :Energy deposition kernels; volume overlap algorithm; radiotherapy planning; photon pencil beams; treatment optimization; biological treatment objectives; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : In recent years, the use of optimization algorithms in radiation therapy planning has increased dramatically. All optimization algorithms as well as most modern implementations of conventional therapy planning, use energy deposition kernels as a fundamental part of the calculations. LÄS MER

  4. 3. Monte Carlo particle transport codes for ion beam therapy treatment planning : Validation, development and applications

    Författare :Till Tobias Böhlen; Irena Gudowska; Oliver Jäkel; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Monte Carlo; ion beam therapy; treatment planning; cancer therapy; microdosimetry; Medical Radiation Physics; medicinsk strålningsfysik;

    Sammanfattning : External radiotherapy with proton and ion beams needs accurate tools for the dosimetric characterization of treatment fields. Monte Carlo (MC) particle transport codes, such as FLUKA and GEANT4, can be a valuable method to increase accuracy of dose calculations and to support various aspects of ion beam therapy (IBT), such as treatment planning and monitoring. LÄS MER

  5. 4. Indirect Radiohalogenation of Targeting Proteins : Labelling Chemistry and Biological Characterisation

    Författare :Anna Orlova; Hans Lundqvist; Jörgen Carlsson; Lars Gedda; Jacek Capala; D.Scott Wilbur; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; radiohalogenation; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Sammanfattning : In about half of all newly diagnosed cancer cases, conventional treatment is not adequately curative, mainly due to the failure of conventional techniques to find and kill residual cells and metastases, which might consist of only a few malignant cells, without causing unacceptable complications to healthy tissue. To solve the problem a more selective delivery of cytotoxic substances to tumour cells is needed. LÄS MER

  7. 5. Wastewater discharges and microbial variability in a surface water source

    Författare :Johan Åström; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; faecal indicators; pathogens; drinking-water; microbial risk assessment; variability; rainfall; catchment; wastewater; surface water; Hazardous events;

    Sammanfattning : Planning for drinking-water safety in surface waters includes a systematic assessment of hazards in the catchment, and microbial contamination is considered a major health risk. The aim of this thesis was to identify and characterize microbial hazardous events reported for River Göta älv, Sweden. LÄS MER