Sökning: "biological treatment objectives"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden biological treatment objectives.

  1. 1. Modeling normal and malignant hematopoiesis in vitro. To screen for extrinsic regulators and differentiation therapy

    Författare :Simon Hultmark; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acute myeloid leukaemia; Hematologi; stem cells; differentiation induction; leukaemia; treatment; small molecule drugs; PKC; FLT3; shRNA; small molecule inhibitor; Small Molecule Libraries; MEK ERK pathway; natural product; co-culture; drug screening; combination therapy;

    Sammanfattning : The incredible thing with blood stem cells, also known as hematopoietic stem cells (HSC), is that they can restore normal hematopoiesis in patients that need a new blood system. Since a prerequisite for successful transplantation is immune compatibility, it requires large donor registries to find a suitable match for a recipient. LÄS MER

  3. 2. Molecular Breeding of Sugar Beet, Transformation, Transgene silencing, Virus and Herbicide resistance

    Författare :Marie Mannerlöf; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Agrobacterium tumefaciens; BNYVV; coat protein; CP4epsps; gene silencing; glyphosate; herbicide; rhizomania; transformation; sugar beet; Beta vulgaris L.; virus; Plant biochemistry; Växtbiokemi;

    Sammanfattning : The main objectives in sugar beet breeding, are to improve yield, quality and to develop disease resistance. The disease resistance may be developed either by conventional, or molecular breeding techniques. The molecular breeding techniques include, methods to genetically engineer plants for expression of introduced genes. LÄS MER

  4. 3. The role of exocrine pancreas for feed intake and growth. Studies in a model with exocrine pancreatic insufficient young pigs

    Författare :Olexandr Fedkiv; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; exocrine pancreatic insufficiency; pigs; pancreatic duct ligation; adaptation;

    Sammanfattning : Exocrine pancreatic insufficiency (EPI), resulting from disease (e.g. cystic fibrosis, chronic pancreatitis) or surgery (e.g. LÄS MER

  5. 4. Development and application of composite energy deposition kernels for photon therapy planning

    Författare :Anders Eklöf; Simo Hyödynmaa; Stockholms universitet; []
    Nyckelord :Energy deposition kernels; volume overlap algorithm; radiotherapy planning; photon pencil beams; treatment optimization; biological treatment objectives; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : In recent years, the use of optimization algorithms in radiation therapy planning has increased dramatically. All optimization algorithms as well as most modern implementations of conventional therapy planning, use energy deposition kernels as a fundamental part of the calculations. LÄS MER

  7. 5. Antibiotic interactions and selection for resistance in biofilms

    Författare :Po-Cheng Tang; Dan I. Andersson; Karin Hjort; Mark Webber; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibiotics; Mikrobiologi; Microbiology;

    Sammanfattning : The challenges posed by antibiotic-resistant bacteria in treating infections, particularly those associated with biofilms, require a deeper understanding of this lifestyle and its connection to resistance selection. Additionally, gaining insights into drug interactions is crucial for enhancing combination treatment efficacy and mitigating resistance development. LÄS MER