Sökning: "Iuliana Toma-Dasu"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Iuliana Toma-Dasu.

  1. 1. Theoretical modelling of tumour oxygenation and influences on treatment outcome

    Författare :Iuliana Toma-Dasu; Mikael Karlsson; Svensson Hans; J F Fowler; Borivoj Vojnovic; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; Computer simulation; Electrode; Polarographic measurements; Tumour oxygenation; Hypoxia; Strålningsvetenskap; Radiation biology; Strålningsbiologi; radiofysik; radiation physics;

    Sammanfattning : One of the main problems in curing cancer resides in the different microenvironment existing in tumours compared to the normal tissues. The mechanisms of failure are different for radiotherapy and chemotherapy, but they all relate to the poor blood supply known to exist in tumours. LÄS MER

  2. 2. Advanced Machine Learning Methods for Oncological Image Analysis

    Författare :Mehdi Astaraki; Chunliang Wang; Örjan Smedby; Iuliana Toma-Dasu; Bjoern Menze; KTH; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medical Image Analysis; Machine Learning; Deep Learning; Survival Analysis; Early Response Assessment; Tumor Classification; Tumor Segmentation; Medicinsk teknologi; Medical Technology;

    Sammanfattning : Cancer is a major public health problem, accounting for an estimated 10 million deaths worldwide in 2020 alone. Rapid advances in the field of image acquisition and hardware development over the past three decades have resulted in the development of modern medical imaging modalities that can capture high-resolution anatomical, physiological, functional, and metabolic quantitative information from cancerous organs. LÄS MER

  3. 3. Optimization of brachytherapy for cervical cancer using inverse planning algorithms

    Författare :Lucilio dos Santos Matias; Iuliana Toma-Dasu; Brígida da Costa Ferreira; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Brachytherapy; treatment planning optimization; IPSA; HIPO; radiobiology; complicationfree; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : Carcinoma of the cervix is a global problem. Brachytherapy (BT) is one of the mainradiation therapy components used in the management of cervical cancer. LÄS MER

  4. 4. Averaged linear energy transfer and other beam quality descriptors inr elation to relative biological effectiveness

    Författare :Fredrik Kalholm; Niels Bassler; Iuliana Toma-Dasu; Emanuele Scifoni; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; LET; RBE; LQ-model; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : In radiotherapy with protons, a constant relative biological effectiveness (RBE) of 1.1 is traditionally applied, i.e. protons are assumed to be 10\% more effective than photons in killing cells. LÄS MER

  5. 5. Time, dose and fractionation: accounting for hypoxia in the search for optimal radiotherapy treatment parameters

    Författare :Emely Kjellsson Lindblom; Iuliana Toma-Dasu; Peter Wersäll; David J Carlson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Hypoxia; radiobiological modelling; radiotherapy; functional imaging; Medical Radiation Physics; medicinsk strålningsfysik;

    Sammanfattning : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. LÄS MER