Sökning: "benzo[a]pyrene"

Visar resultat 26 - 30 av 43 avhandlingar innehållade ordet benzo[a]pyrene.

  1. 26. Determination of OPAHs and PAHs in Particulate Matter from Ambient Air and Engine Emissions : Multidimensional Chromatography

    Författare :Trifa Mohammad Ahmed; Roger Westerholm; Peter Haglund; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Particulate matter (PM) is an air pollutant that seriously impacts human health. Epidemiological studies have shown associations between human exposure to urban air PM and lung cancer, respiratory and cardiovascular diseases. LÄS MER

  2. 27. Measurement of primary DNA damage in individual cells from humans and mice using the alkaline single cell gel electrophoresis assay

    Författare :Hamid Vaghef; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; arbets- och miljömedicin; Occupational and Environmental Medicine;

    Sammanfattning : Primary DNA damage is considered to be an important step in the development of tumours and itmay also serve as a biomarker of genotoxic stress. Measurement of DNA strand breaks in peripherallymphocytes can yield useful information about the suitability of these cells for biomonitoring purposesand subsequently risk assessment. LÄS MER

  3. 28. Exposure to some carcinogenic compounds in air, with special reference to wood smoke

    Författare :Pernilla Gustafson; Göteborgs universitet; []
    Nyckelord :formaldehyde; acetaldehyde; 1; 3-butadiene; benzene; polycyclic aromatic hydrocarbons; particulate matter; domestic wood burning; exposure assessment; personal exposure; experimental study;

    Sammanfattning : The general population is exposed to air pollutants in both indoor and outdoor air from many different sources, including traffic, biomass burning, industries, cigarette smoking, and certain building materials. Air pollutants can cause a variety of health effects such as cancer and respiratory and cardiovascular diseases. LÄS MER

  4. 29. Mdm2 phosphorylations : characterization and applications

    Författare :Maria Malmlöf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer is a widespread disease. In spite of all research resulting in new improved therapies, there are still many tumors that cannot be cured. To oppose that, also a preventive research approach is important with goals such as decreasing the human exposure to carcinogens. LÄS MER

  5. 30. Xenobiotics-induced phosphorylations of MDM2

    Författare :Gerd Pääjärvi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of the present study was to characterize the Mdm2 and p53 responses induced by DNA damaging xenobiotics and how these responses can be modified by non-genotoxic xenobiotics. During control conditions cellular levels of p53 are low. The level is regulated by Mdm2 and Mdm2 and p53 forms an autoregulatory loop. LÄS MER