Sökning: "benzo[a]pyrene"
Visar resultat 26 - 30 av 43 avhandlingar innehållade ordet benzo[a]pyrene.
26. Determination of OPAHs and PAHs in Particulate Matter from Ambient Air and Engine Emissions : Multidimensional Chromatography
Sammanfattning : Particulate matter (PM) is an air pollutant that seriously impacts human health. Epidemiological studies have shown associations between human exposure to urban air PM and lung cancer, respiratory and cardiovascular diseases. LÄS MER
27. Measurement of primary DNA damage in individual cells from humans and mice using the alkaline single cell gel electrophoresis assay
Sammanfattning : Primary DNA damage is considered to be an important step in the development of tumours and itmay also serve as a biomarker of genotoxic stress. Measurement of DNA strand breaks in peripherallymphocytes can yield useful information about the suitability of these cells for biomonitoring purposesand subsequently risk assessment. LÄS MER
28. Exposure to some carcinogenic compounds in air, with special reference to wood smoke
Sammanfattning : The general population is exposed to air pollutants in both indoor and outdoor air from many different sources, including traffic, biomass burning, industries, cigarette smoking, and certain building materials. Air pollutants can cause a variety of health effects such as cancer and respiratory and cardiovascular diseases. LÄS MER
29. Mdm2 phosphorylations : characterization and applications
Sammanfattning : Cancer is a widespread disease. In spite of all research resulting in new improved therapies, there are still many tumors that cannot be cured. To oppose that, also a preventive research approach is important with goals such as decreasing the human exposure to carcinogens. LÄS MER
30. Xenobiotics-induced phosphorylations of MDM2
Sammanfattning : The aim of the present study was to characterize the Mdm2 and p53 responses induced by DNA damaging xenobiotics and how these responses can be modified by non-genotoxic xenobiotics. During control conditions cellular levels of p53 are low. The level is regulated by Mdm2 and Mdm2 and p53 forms an autoregulatory loop. LÄS MER