Sökning: "benzo[a]pyrene"
Visar resultat 6 - 10 av 43 avhandlingar innehållade ordet benzo[a]pyrene.
6. Oxidation and conjugation of drugs in hepatocytes with emphasis on benzo[a]pyrene activation
Sammanfattning : .... LÄS MER
7. A Gill Filament EROD Assay : Development and Application in Environmental Monitoring
Sammanfattning : A gill filament-based assay for the cytochrome P450 1A (CYP1A)-catalysed activity ethoxyresorufin O-deethylase (EROD) was developed in rainbow trout (Oncorhynchus mykiss) and applied to Atlantic salmon (Salmo salar), Arctic charr (Salvelinus alpinus), Atlantic cod (Gadus morhua), saithe (Pollachius virens), and spotted wolffish (Anarhichas minor). Exposure to waterborne β-naphthoflavone (βNF; 10-6 M) induced branchial EROD activity in all species but the spotted wolffish. LÄS MER
8. Automation, hyphenation and multidimensional chromatography for PAH analysis : Analytical techniques to simplify sample complexity
Sammanfattning : One group of organic environmental pollutants which are potentially hazardous to human health is polycyclic aromatic hydrocarbons (PAHs). These compounds consist of two or more benzene rings in their structure among which benzo[a]pyrene (B[a]P) is classified as a human carcinogen. LÄS MER
9. The in vivo metabolism of Benzo(a)pyrene studied by chromatography in combination with mass spectrometry
Sammanfattning : Polycyclic aromatic hydrocarbons (PAHs) constitute a large class of chemicals with widespread occurrence in the environment. It is essentially impossible to avoid exposure to these substances on a daily basis. LÄS MER
10. Biomarkers of internal exposure/dose : Methods to quantify adducts to protein and DNA by LC/MS studied with benzo[a]pyrene and isocyanates
Sammanfattning : This thesis focuses on methods for quantification by liquid chromatography/mass spectrometry (LC/MS) of specific biomarkers for internal dose of chemicals which induce toxicity through their electrophilic reactivity. In vivo such compounds are short-lived, and could feasibly be measured as their reaction products (adducts) with biomacromolecules. LÄS MER