Sökning: "antiviral drugs"

Visar resultat 36 - 40 av 59 avhandlingar innehållade orden antiviral drugs.

  1. 36. Discovery of Secondary Metabolites from Rwandese Medicinal Plants : Isolation, Characterization and Biological Activity

    Författare :Daniel Umereweneza; Máté Erdélyi; A Gogoll; Théoneste Muhizi; Yngve Stenstrøm; Uppsala universitet; []
    Nyckelord :Natural products; Nuclear Magnetic Resonance NMR ; Dihydrochalcones; Iridoids; Silphiperfolanols; Pyrrolizidine alkaloids PAs ; Rwandese Medicinal Plants; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : Plants have served as the principal source of medicines in different parts of the world through the ages. Herb-derived medicines have been used as decoctions, infusions, tinctures or single substance drugs. LÄS MER

  3. 37. Antiretroviral treatment of HIV-1 in the central nervous system

    Författare :Aylin Yilmaz; Göteborgs universitet; []
    Nyckelord :HIV-1; cerebrospinal fluid; antiretroviral treatment; lopinavir; saquinavir; nelfinavir; neopterin; beta-2-microglobulin; HIV-1 RNA; IgG index; blood-brain barrier; albumin ratio; ultra-ultra sensitive PCR;

    Sammanfattning : HIV-1 invades the central nervous system (CNS) early in the infectious course. It establishes a chronic progressive infection, and triggers an intrathecal immune response. If left untreated, a majority of patients will develop neurological complications, caused by opportunistic pathogens or HIV-1 itself. LÄS MER

  4. 38. HIV-1 reverse transcriptase as a target in the development of specific enzyme inhibitors

    Författare :Hong Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human immunodeficiency virus type I (HIV-I), which causes the acquired immunodeficiency syndrome (AIDS), begins its intracellular infection life cycle with reverse transcription of its plus-strand RNA genome into a double-stranded proviral DNA intermediate which is integrated into the host chromosome inducing a persistent infection. A virally encoded enzyme, reverse transcriptase (RT), carries out the reverse transcription process by performing all three enzymatic activities, i. LÄS MER

  5. 39. Modelling Sexual Interactions : Sexual behaviour and the spread of sexually transmitted infections on dynamic networks

    Författare :Disa Hansson; Tom Britton; Fredrik Liljeros; KaYin Leung; Janneke Heijne; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mathematical modelling; Sexually transmitted infections; Egocentric network analysis; Dynamic networks; Sexual behaviour; HIV; Statistical inference; Mathematical Statistics; matematisk statistik;

    Sammanfattning : In this thesis we develop statistical and mathematical models to study different factors of relevance for the spread of sexually transmitted infections (STIs). Two special interest groups for STI interventions are considered: sexually active youths and men who have sex with men (MSM). LÄS MER

  7. 40. Immune response during hepatitis B virus infection and reconstitution of HBV-specific immunity using T cells redirected against HBV

    Författare :Sarene Koh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hepatitis B is one of the most prevalent viral diseases worldwide and is a major public health concern, particularly in Asia. Of the 350 million people suffering from chronic hepatitis B virus (HBV) infection worldwide, approximately 75% are found in Asia. LÄS MER