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Visar resultat 21 - 25 av 438 avhandlingar som matchar ovanstående sökkriterier.

  1. 21. Novel starch types : molecular diversity for future applications

    Författare :Shishanthi Jayarathna; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : This thesis investigated molecular changes in potato starch achieved through targeted mutations in the starch synthesis pathway. CRISPR/Cas9 was used to induce mutations in starch branching enzyme genes (SBE), with or without mutations in granule bound starch synthase gene (GBSS). LÄS MER

  3. 22. Studies on the Polymorphism and Transcriptional Regulation of the ABO and P1PK Histo-blood Group Genes

    Författare :Britt Thuresson; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood group; ABO; A4GALT; P1PK; Gene regulation; Enhancer;

    Sammanfattning : Antigens of the clinically important ABO and P1PK blood group systems are carbohydrate structures. Thus the underlying genes do not encode antigens directly but glycosyltransferases that add specific sugar molecules to selected precursor chains. LÄS MER

  4. 23. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus

    Författare :Bo Johanneson; Jean Pierre Hugot; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Association analysis; Candidate gene; Complex disease; Genome scan; Linkage analysis; Mapping; Susceptibility genes; Systemic lupus erythematosus; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. LÄS MER

  5. 24. Molecular genetics of human carbohydrate defined blood groups. Studies of the ABO and P blood group systems

    Författare :Rudi Steffensen; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABO blood group system; P blood group system; carbohydrate antigen; DNA; sequencing; populations studies; expression studies;

    Sammanfattning : The aim of this study was to explore the molecular genetics of the carbohydrate defined blood group ABO and P systems.The blood group ABO system is the clinically most significant system in transfusion medicine. Using modern molecular biology, a number of the ABO alleles have been characterized. LÄS MER

  7. 25. Erasing Fear : Effect of Disrupting Fear Memory Reconsolidation on Central and Peripheral Nervous System Activity

    Författare :Thomas Ågren; Mats Fredrikson; Tomas Furmark; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Memory reconsolidation; fear conditioning; serotonin; dopamine; polymorphism; gene; exposure therapy; fMRI; amygdala;

    Sammanfattning : Fear memories, here defined as learned associations between a stimulus and a physiological fear reaction, are formed through fear conditioning. In animals, fear memories, present in the lateral amygdala, undergo reconsolidation after recall. LÄS MER