Sökning: "adipose tissue depots"

Visar resultat 11 - 15 av 34 avhandlingar innehållade orden adipose tissue depots.

1. 11. Estrogen and Glucocorticoid Metabolism

   Författare :Therése Andersson; Tommy Olsson; Cecilia Mattsson; Ingegerd Söderström; Jonas Burén; Agneta Holmäng; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11β-Hydroxysteroid Dehydrogenase Type 1; Estrogen; Cortisol; Adipose tissue; Liver; Menopause; Ovariectomy; Adipocyte; Estrogen Receptor β; Endocrinology; Endokrinologi; medicin; Medicine;

   Sammanfattning : Background: Cardiovascular disease (CVD) is the leading cause of death among women in Sweden. The risk of CVD increases rapidly after the menopause. A major contributing factor may be the redistribution of adipose tissue, from the peripheral to central depots, associated with menopause. LÄS MER

3. 12. The role of galectin-1 in type 2 diabetes. Clinical and experimental studies

   Författare :Emanuel Fryk; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galectin-1; type 2 diabetes; human; adipose tissue; metabolism;

   Sammanfattning : Aim: The purpose of this thesis was to identify a new agent in the subcutaneous adipose tissue and assess its clinical potential in the context of type 2 diabetes. Study I: Through a combination of microdialysis and mass-spectrometry, we found increased galectin-1 levels in the subcutaneous adipose tissue in a small experimental study of 15 men with and without type 2 diabetes. LÄS MER

4. 13. Alterations in peripheral glucocorticoid metabolism : effects of weight changes

   Författare :Kotryna Simonyté; Cecilia Mattsson; Bo Angelin; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11ß Hydroxysteroid dehydrogenase 1; obesity; glucocorticoids; cortisol; phosphoenolpyruvate carboxykinase; adipose tissue; liver; Endocrinology; Endokrinologi; medicin; Medicine;

   Sammanfattning : Background: An important role has been suggested for tissue-specific glucocorticoid metabolism in the development of obesity and its complications. 11ß hydroxysteroid dehydrogenase 1 (11ßHSD1) is an enzyme that catalyzes the interconversion of biologically inactive cortisone to active cortisol, thereby regulating its access to glucocorticoid receptors in target tissues. LÄS MER

5. 14. Protein and mRNA Studies of Rat FA1/Pref-1/dlk

   Författare :Gabriella Persdotter Hedlund; Jann Hau; Carina Carlsson; Torgny Stigbrand; Uppsala universitet; []
   Nyckelord :Laboratory animals; Preadipocyte factor 1; delta like protein; Fetal antigen 1; Goto-Kakizaki; Zucker; adipokines; adipose tissue; diabetes; obesity; Försöksdjursvetenskap;

   Sammanfattning : The timing of cell differentiation is important for development and renewal of well functioning organs and tissues. One protein involved in this process is Preadipocyte factor 1 (Pref-1). Most likely, the role of this protein is to maintain cells in an undifferentiated state. LÄS MER

7. 15. Significance of adipose tissue characteristics for development of metabolic complications in obesity

   Författare :Daniel P Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Obesity is closely related to development of insulin resistance and dyslipidemia. Intrinsic properties of adipose tissue are also of great importance for obesity related comorbidity. LÄS MER