Sökning: "adipokines"

Visar resultat 16 - 20 av 34 avhandlingar innehållade ordet adipokines.

  1. 16. The regulatory role of microRNA in human adipocytes and their link to insulin resistance

    Författare :Yasmina Belarbi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : White adipose tissue (WAT) is a highly plastic organ which secretes a large number of peptide factors termed adipokines. Increased caloric intake increases WAT mass which results in marked alterations in the secretory pattern. This may be mediated via both transcriptional and post-transcriptional mechanisms. LÄS MER

  3. 17. Adipose tissue as an active organ : blood flow regulation and tissue-specific glucocorticoid metabolism

    Författare :Jonas Andersson; Tommy Olsson; Stefan Söderberg; Sverker Jern; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11β-hydroxysteroid dehydrogenase type 1; adipose tissue; autonomic nervous system; blood flow; cortisol; nitric oxide; weight loss.; medicin; Medicine;

    Sammanfattning : Background: Despite advances in the treatment of atherosclerosis, cardiovascular disease is the leading cause of death worldwide. With the population getting older and more obese, the burden of cardiovascular disease may further increase. LÄS MER

  4. 18. Role of immune mediators in metabolic syndrome and atherosclerosis

    Författare :Daniela Strodthoff; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Obesity is increasingly becoming a problem worldwide. Both location and metabolic activity of visceral and subcutaneous white adipose tissue (WAT) differ. Visceral fat is highly vascularized resulting in increased blood supply and increased infiltration of inflammatory immune cells such as macrophages, T cells and even B cells. LÄS MER

  5. 19. Immunometabolic patterns in psychiatric disease

    Författare :Mikaela Syk; Janet Cunningham; Lisa Ekselius; Annica J. Rasmusson; Robert Fredriksson; Brenda Penninx; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; Human; Autoimmunity; Cytokines; Inflammation; Adiponectin; Leptin; CNS damage; NfL; Tau; GFAp; Biomarkers; Depression; Neuroticism; Bulimia nervosa; Psychiatry; Psykiatri;

    Sammanfattning : Many forms of immune system dysregulation are linked to psychiatric disorders. This thesis examines specific types of immune dysregulation in broad cohorts with psychiatric disease. The first section focuses on adipokines and other immunometabolic biomarkers and their interaction with state vs. trait symptoms. LÄS MER

  7. 20. Barnfetma och Metabola Syndromet hos förskolebarn - tidiga faktorer och identifiering av riskindivider från ett longitudinellt perspektiv : Childhood Obesity and Metabolic Syndrome in Preschool Children - Early markers and identification of individuals at increased risk in a longitudinal perspective

    Författare :Emma Kjellberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adiponectin; childhood obesity; insulin resistance; leptin; metabolic syndrome; n-6 fatty acids; Subcutaneous adipose tissue; Visceral adipose tissue; waist circumference;

    Sammanfattning : Background: Overweight and obesity have increased worldwide and affect children at ever younger ages, resulting in cardiovascular disease and type 2 diabetes even in adolescents. This illustrates the importance of identifying children at risk at an early stage. Aim: To study metabolic health in preschool children. LÄS MER