Sökning: "NfL"

Visar resultat 1 - 5 av 57 avhandlingar innehållade ordet NfL.

  1. 1. The diagnostic challenge of Parkinsonian syndromes. Clinical and laboratory evaluation

    Författare :Björn Holmberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; MSA; PSP; autonomic tests; differential diagnosis; levodopa test; NFL; GFAP;

    Sammanfattning : Background: The differentiation between Parkinson's disease (PD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) may be difficult, but it is important for prognostic and therapeutic purposes. The aim of this study was to evaluate the differential diagnostic capacity of laboratory tests in a population of patients fulfilling strict clinical criteria for these disorders. LÄS MER

  3. 2. Studies of biochemical brain damage markers in patients at a neurointensive care unit

    Författare :Karin Nylén; Göteborgs universitet; []
    Nyckelord :subarachnoid haemorrhage; traumatic brain injury; outcome; NFL; S100; GFAP; biochemical brain damage markers;

    Sammanfattning : Physical examination is the basic and most important tool in medical practice. However, at a neurointensive care unit, neurological status can sometimes be difficult to evaluate due to sedation or impaired consciousness. Repeated radiology may not always be feasible. LÄS MER

  4. 3. Prediction value of genetic and neuromarkers in blood and liquor in patients with severe traumatic brain injury

    Författare :Martin Öst; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; outcome; NFL; GFAP; tau; β-amyloid; apolipoprotein E; biochemical neuromarkers;

    Sammanfattning : Background: Severe traumatic brain injury (sTBI) is the most common cause of mortality in young adults. sTBI induces variable brain damage, invisible in Computer Tomographic scans early post-trauma. Further, neurology is difficult to evaluate in sedated patients. LÄS MER

  5. 4. Spinal cord ischemia after advanced endovascular aortic repair. Prevention, risk factors and patient-reported outcomes

    Författare :Irma Mehmedagic; Vaskulära sjukdomar - kliniska studier; []
    Nyckelord :Spinal cord ischemia; Cerebrospinal fluid drainage; Endovascular treatment; Thoracoabdominal aortic aneurysm; Aortic dissection; Life satisfaction; Biomarkers; NFL; T-tau;

    Sammanfattning : .... LÄS MER

  7. 5. Immunometabolic patterns in psychiatric disease

    Författare :Mikaela Syk; Janet Cunningham; Lisa Ekselius; Annica J. Rasmusson; Robert Fredriksson; Brenda Penninx; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; Human; Autoimmunity; Cytokines; Inflammation; Adiponectin; Leptin; CNS damage; NfL; Tau; GFAp; Biomarkers; Depression; Neuroticism; Bulimia nervosa; Psychiatry; Psykiatri;

    Sammanfattning : Many forms of immune system dysregulation are linked to psychiatric disorders. This thesis examines specific types of immune dysregulation in broad cohorts with psychiatric disease. The first section focuses on adipokines and other immunometabolic biomarkers and their interaction with state vs. trait symptoms. LÄS MER