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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Acute Myocardial Infarction: The Relationship between Duration of Ischaemia and Infarct Size in Humans - Assessment by MRI and SPECT

    Författare :Erik Hedström; Lund Klinisk fysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Fysiologi; Physiology; humans; cardiac troponin T; creatine kinase isoenzyme MB; delayed contrast-enhanced magnetic resonance imaging; single photon emission computed tomography; myocardial perfusion; myocardial infarct size; myocardium at risk; duration of ischaemia; Kardiovaskulära systemet;

    Sammanfattning : The effect of duration of ischaemia on final infarct size is well established in animal studies, but not fully evaluated in humans. Delayed contrast-enhanced magnetic resonance imaging (DE-MRI) can be used to distinguish between viable and non-viable myocardium and thus to quantify infarct size. LÄS MER

  2. 2. Artificial neural networks for assessment of patients with suspected acutemyocardial infarction

    Författare :Johan Ellenius; Uppsala universitet; []
    Nyckelord :Medical sciences; Artificial neural network; decision-support systems; transferability; acute myocardial infarction; infarct size; nondiagnostic ECG; myoglobin; CK-MB; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; medicinsk informatik; medicinsk informatik;

    Sammanfattning : An early diagnosis within the first hours after onset of symptoms is essential for the optimal treatment of patients admitted with chest pain of suspected cardiac origin. In the majority of patients, the 12-lead ECG is nondiagnostic on admission. LÄS MER

  3. 3. Cardiac Troponins in Patients with Suspected or Confirmed Acute Coronary Syndrome : New Applications for Biomarkers in Coronary Artery Disease

    Författare :Kai Eggers; Bertil Lindahl; Stefan James; Paul Collinson; Uppsala universitet; []
    Nyckelord :Internal medicine; Ischemic heart disease; Acute myocardial infarction; Troponin; Natriuretic peptide; CRP; Cystatin C; Artificial neural network; Point of care measurements; Risk prediction; Invärtesmedicin;

    Sammanfattning : The cardiac troponins are the biochemical markers of choice for the diagnosis of acute myocardial infarction (AMI) and risk prediction in patients with acute coronary syndrome (ACS). In this thesis, the role of early serial cardiac troponin I (cTnI) testing was assessed in fairly unselected patient populations admitted because of chest pain and participating in the FAST II-study (n=197) and the FASTER I-study (n=380). LÄS MER

  4. 4. Evaluation of risk factor modification management in patients with coronary heart disease and patients´ experiences of secondary prevention

    Författare :Mona From Attebring; Göteborgs universitet; []
    Nyckelord :Coronary heart disease; myocardial infarction; secondary prevention; risk factor modification; smoking cessation; validation; predictors; patients experiences; nursing;

    Sammanfattning : Aim: To evaluate management of risk factor modification among patients suffering from coronary heart disease and to explore patients experiences of secondary prevention. Methods: After establishing a secondary prevention programme, patients were offered follow-up visits to a nurse, one year after the coronary event for evaluation of various risk factors associated with recurrence (I, II). LÄS MER

  5. 5. Targeted multiplex proteomics for risk stratification in patients with cardiovascular disease

    Författare :Emma Skau; Pär Hedberg; Jerzy Leppert; Johan Ärnlöv; Eva Swahn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiovascular disease; proteomics; myocardial infarction; peripheral arterial disease; biomarker; GDF-15; Cardiology; Kardiologi;

    Sammanfattning : Risk stratification is valuable in patients with cardiovascular disease (CVD). Proteins involved in different pathophysiological processes in atherosclerosis have shown prognostic capacity. A new technology, Proximity Extension Assay (PEA), enables the simultaneous analysis of numerous plasma proteins from a minimal amount of plasma. LÄS MER