Sökning: "acute lung injury"

Visar resultat 41 - 45 av 64 avhandlingar innehållade orden acute lung injury.

  1. 41. Aspects on ventilation induced stress and strain on regional and global inflammation in experimental acute respiratory distress syndrome

    Författare :Jaime Retamal Montes; Anders Larsson; Göran Hedenstierna; Alejandro Bruhn; Björn Jonson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ARDS; VILI; respiratory rate; strain; PET;

    Sammanfattning : Mechanical ventilation (MV) is a life-saving therapy in acute respiratory distress syndrome (ARDS), a condition that affects 3000 patients/year in Sweden with a mortality rate of about 40%. However, MV may induce or worsen lung injury causing “ventilator-induced lung injury (VILI)”. LÄS MER

  2. 42. Development of multi-cellular human lung models to study inflammatory mechanisms and cell-cell interactions

    Författare :Jie Ji; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : It is well known that exposure to toxicants in the environment is associated with a wide range of health effects. The airway epithelium which forms the first line of defense, plays critical roles in the defence against inhaled particles, pathogens and toxic agents. LÄS MER

  3. 43. Inverse ration ventilation : experimental studies on pulmonary integrity and gas exchange

    Författare :Ulf Ludwigs; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :respiration; artificial gas exchange lung function acute respiratory distress syndromeacute lung injury inverse ratio ventilation ventilator induced lung injury intrinsic PEEP lungclearance;

    Sammanfattning : In this thesis, pulmonary and circulatory effects of inverse ratio ventilation (IRV) have been studied experimentally. Comparisons have been made between volume and pressure controlled IRV and conventional ventilation under conditions of equal minute ventilation and end-expiratory alveolar pressure levels. LÄS MER

  4. 44. Adjuvant therapies to fluid resuscitation in experimental sepsis : Intervention studies in models of ARDS and peritonitis

    Författare :Annelie Barrueta Tenhunen; Gaetano Perchiazzi; Johanna Hästbacka; Uppsala universitet; []
    Nyckelord :Acute respiratory distress syndrome; edema formation; peritonitis; sepsis; fluid resuscitation; animal model; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : Fluid resuscitation is essential to antagonize the deleterious effects of tissue hypo-perfusion in sepsis. If not thoroughly monitored and individually tailored, fluid therapy increases the risk of volume overload. Volume overload is associated with higher mortality in sepsis. LÄS MER

  5. 45. Functional residual capacity – development of new monitoring techniques for critically ill patients

    Författare :Cecilia Olegård; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FRC functional residual capacity EELV end-expiratory lung volume volume dependent compliance VDC acute respiratory failure recruitment manouvre PEEP;

    Sammanfattning : Functional residual capacity (FRC) and end-expiratory lung volume (EELV) are important parameters for respiratory monitoring in critically ill adult and paediatric patients. Until now we have lacked clinically useful methods to measure these lung volumes. LÄS MER