Sökning: "VILI"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet VILI.

1. 1. Aspects on ventilation induced stress and strain on regional and global inflammation in experimental acute respiratory distress syndrome

   Författare :Jaime Retamal Montes; Anders Larsson; Göran Hedenstierna; Alejandro Bruhn; Björn Jonson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ARDS; VILI; respiratory rate; strain; PET;

   Sammanfattning : Mechanical ventilation (MV) is a life-saving therapy in acute respiratory distress syndrome (ARDS), a condition that affects 3000 patients/year in Sweden with a mortality rate of about 40%. However, MV may induce or worsen lung injury causing “ventilator-induced lung injury (VILI)”. LÄS MER

3. 2. Minimal volume ventilation in lung injury : With special reference to apnea and buffer treatment

   Författare :Staffan Höstman; Anders Larsson; Hans Hjelmqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; VILI; THAM; buffers; apneic oxygenation; respiratory acidosis; hypercapnia; low volume ventilation; mechanical ventilation; ultra-protective ventilation; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : A fairly large portion of patients receiving surgical or intensive care will need mechanical ventilation at some point. The potential ventilator-induced lung injury (VILI) is thus of interest. One of the main causal factors in VILI is the cyclic energy shifts, i.e. LÄS MER

4. 3. Cross-modal Imaging in Lung Research: From µCT dosimetry to synchrotron phase contrast microtomography biomechanical insights in preclinical lung injury models

   Författare :Richard Deyhle Jr; Malmö Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thermoluminescent Dosimetry; Optically stimulated luminescence OSL ; Computed tomography CT ; 4DCT; Phantoms; Imaging; X-rays; pre-clinical models; Pre-clinical; dosimetry: physical basis; biomedical strain; lung injury; mechanical ventilation; inflammation; lung function; synchrotron; histology; acute respiratory distress syndrome ARDS ; Ventilator Inudced Lung Injury VILI ; Histology; Forced Oscillation Technique FOT ; Divergence Theorem; Registration techniques;

   Sammanfattning : Lung diseases continue to present a large burden to public health, especially in industrialized countries. For abetter understanding of the underlying patho-mechanisms in lung related diseases as well as for testing theefficacy of novel therapies, preclinical studies in animal models are indispensable. LÄS MER

5. 4. Tools for protective lung ventilation. The elastic pressure-volume curve and aspiration of dead space

   Författare :Edoardo De Robertis; Lund Klinisk fysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical physics; radiology; tomografi; medicinsk instrumentering; radiologi; Klinisk fysiologi; tomography; medical instrumentation; Respiratory system; Andningsorganen;

   Sammanfattning : Ventilator-induced lung injury (VILI) may contribute to morbidity and mortality of acute lung injury (ALI). Lung protective ventilation (LPV), that reduces VILI, may involve low tidal volume (Vt). Particularly low Vt is possible if dead space ventilation is reduced e.g. LÄS MER

7. 5. Regional Lung Kinetics of Ventilator-Induced Lung Injury and Protective-Ventilation Strategies Studied by Dynamic Positron Emission Tomography

   Författare :João Batista Borges; Anders Larsson; Giacomo Bellani; Uppsala universitet; []
   Nyckelord :[18F]fluoro-2-deoxy-D-glucose; positron emission tomography; acute pulmonary inflammation; acute respiratory distress syndrome; mechanical ventilation; ventilator-induced lung injury;

   Sammanfattning : Mechanical ventilation in itself can harm the lung and cause ventilator-induced lung injury (VILI), which can induce or aggravate acute respiratory distress syndrome (ARDS). Much debate remains over pivotal concepts regarding the pathophysiology of VILI, especially about the precise contribution, kinetics, and primary role of potential VILI mechanisms. LÄS MER