Sökning: "Nucleobindin Nuc"

Hittade 2 avhandlingar innehållade orden Nucleobindin Nuc.

1. 1. Studies on three matrix molecules in bone and dentin

   Författare :Ulrika Petersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Osteoadherin OSAD ; Nucleobindin Nuc ; Calreticulin CRT ; biomineralization; osteogenesis; dentinogenesis;

   Sammanfattning : The biomineralization of bone and dentin is a complex and dynamic process, involving the formation of an organic framework in which mineral crystals are deposited. The noncollagenous proteins (NCPs) of the organic phase play a central role in the extracellular matrix (ECM) organization and mineralization regulation. LÄS MER

3. 2. Novel non-collagenous modulators of biomineralization in bone and dentin

   Författare :Eszter Somogyi-Ganss; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Calreticulin; nucleobindin; prothrombin; biomineralization; osteogenesis; dentinogenesis;

   Sammanfattning : The formation of mineralized tissues such as bones and teeth is governed on many levels by molecular, genetic, and cellular events to culminate in terminally differentiated cells that secrete a specialized organic matrix, which is later mineralized through the coordinated deposition of calcium phosphate crystals. The formation of this hard tissue phase is tightly regulated by components of the extracellular matrix (ECM), since deviations from this equilibrium result in prevalent, debilitating health problems such as arthritis, vascular calcification, periodontal disease and osteoporosis. LÄS MER