Sökning: "Vaccines"

Visar resultat 26 - 30 av 327 avhandlingar innehållade ordet Vaccines.

  1. 26. The impact of viral vaccines in immunosuppressed and at-risk individuals

    Författare :Anja Rosdahl; Torbjörn Norén; Helena Hervius Askling; Sara Cajander; Leonardus (Leo) Visser; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vaccine; Vaccine failure; Immunocompromised host; Hepatitis A; Tick borne encephalitis; SARS-CoV-2; Innate immunity; Adaptive immunity;

    Sammanfattning : Vaccines have saved millions of lives, but for some individuals with a defective immune system the protection may be uncertain. This thesis aims to assess the immune response following viral vaccines in immunocompromised patients and in other groups at-risk. LÄS MER

  3. 27. Roles in innate immune receptors : host – pathogen interactions and strengthening vaccines

    Författare :Sanna Nyström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During the past decades our knowledge of innate immunology has increased drastically. This has improved our understanding about how innate immune cells can distinguish self from non-self, commensal bacteria from pathogens, and how it affects later adaptive immune responses. LÄS MER

  4. 28. Hsp70 in immunotherapy : a potential vector in cancer and viral vaccines

    Författare :Anne-Marie T Ciupitu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :heat shock protein 70; vaccination; tumour antigens; in vivo protection; T cell activation; adjuvant; LCMV;

    Sammanfattning : New efficient vaccines against cancers and infectious diseases are in demand. In 1993 heat shock protein 70 (hsp70) purified from tumour was shown to elicit tumour protection in mice. It was also shown that the protection was not mediated by the hsp70 itself, but by tumour-specific peptides bound to the molecule. LÄS MER

  5. 29. Novel vaccines and antiviral treatments for enterovirus induced infections and disease

    Författare :Marta Butrym; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Enterovirus infections are common around the world and can impact people’s lives in various ways, causing pancreatitis, myocarditis, common cold and more. This thesis is focused on testing the effectiveness of new vaccines and an antiviral agent in the context of cystic fibrosis (CF) and type 1 diabetes (T1D). LÄS MER

  7. 30. More or Less IgE : Therapeutic Vaccines, Adjuvants and Genes and Their Effect on IgE Levels

    Författare :Anna Ledin; Lars Hellman; Kjell-Olov Grönvik; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; IgE; Immunoglobulin; Atopic allergy; Vaccine; Adjuvant; Dog; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : Immunoglobulin E (IgE) is an important mediator in atopic allergies. This thesis describes the development of a therapeutic vaccine against IgE and its effects in rats and dogs. The development of an assay to determine IgE levels in dogs, and the finding of a chromosome region in rats that affects IgE levels are also reported. LÄS MER