Sökning: "heat shock protein 70"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden heat shock protein 70.

  1. 1. Heat shock proteins as vaccine adjuvants

    Författare :Khaleda Rahman Qazi; Carmen Fernández; Qijun Chen; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heat shock protein; vaccine; adjuvant; BCG; Immunology; Immunologi;

    Sammanfattning : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. LÄS MER

  3. 2. The Interaction Between the Chaperonin GroEL and Human Carbonic Anhydrase II : Protein Folding and Stability Studies

    Författare :Malin Persson; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbonic anhydrase; protein folding; protein stability; chaperone; GroEL; folding mechanism; site-directed spinlabeling; electron paramagnetic resonance EPR ;

    Sammanfattning : The presence of GroEL/ES during the refolding of human carbonic anhydrase II was found to increase the yield of active enzyme from approx. 70 to approx. 100%. This chaperone action on the enzyme could be obtained by adding GroEL alone, and the time course in that case was only moderately slower than the spontaneous process. LÄS MER

  4. 3. Hsp70 nucleotide exchange factor Fes1 is essential for protein quality control in Saccharomyces cerevisiae

    Författare :Naveen Kumar Chandappa Gowda; Claes Andréasson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Heat shock protein 70; molecular chaperone; ubiquitin; nucleotide exchange factor; protein quality control; Cell Biology; cellbiologi;

    Sammanfattning : .... LÄS MER

  5. 4. Mapping ultrastructural effects of proteotoxic stress on S. cerevisiae

    Författare :Katharina Keuenhof; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; yeast; heat shock; stress; electron microscopy; ultrastructure; nuclear envelope budding;

    Sammanfattning : Cells are the basic building blocks of any living being, whether the organism consists of only one, or many cells. The different cellular components interact with one another to maintain the viability of the cell. An essential element of cells are proteins – peptide chains folded into a specific conformation unique to every protein. LÄS MER

  7. 5. Regulation of Hsp70 function by nucleotide-exchange factors

    Författare :Naveen Kumar Chandappa Gowda; Claes Andréasson; Gary Jones; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Heat shock proteins Hsps ; Hsp70; Molecular chaperones; Nucleotide-exchange factors NEFs ; Protein quality control PQC ; Proteostasis; Ubiquitin-proteasome system; Cell Biology; cellbiologi;

    Sammanfattning : Protein folding is the process in which polypeptides in their non-native states attain the unique folds of their native states. Adverse environmental conditions and genetic predisposition challenge the folding process and accelerate the production of proteotoxic misfolded proteins. LÄS MER