Sökning: "Sara Cajander"

Hittade 2 avhandlingar innehållade orden Sara Cajander.

  1. 1. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis

    Författare :Sara Cajander; Jan Källman; Kristoffer Strålin; Bo Söderquist; Per Åkesson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monocyte HLA-DR; sepsis; immunosuppression; bloodstream infection; HLA-DRA; CIITA; qRT-PCR;

    Sammanfattning : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. LÄS MER

  3. 2. The impact of viral vaccines in immunosuppressed and at-risk individuals

    Författare :Anja Rosdahl; Torbjörn Norén; Helena Hervius Askling; Sara Cajander; Leonardus (Leo) Visser; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vaccine; Vaccine failure; Immunocompromised host; Hepatitis A; Tick borne encephalitis; SARS-CoV-2; Innate immunity; Adaptive immunity;

    Sammanfattning : Vaccines have saved millions of lives, but for some individuals with a defective immune system the protection may be uncertain. This thesis aims to assess the immune response following viral vaccines in immunocompromised patients and in other groups at-risk. LÄS MER