Sökning: "TNF-α"

Visar resultat 11 - 15 av 203 avhandlingar innehållade ordet TNF-α.

  1. 11. Omega-3 fatty acid treatment in mild to moderate Alzheimer's disease : results from the OmegAD study

    Författare :Yvonne Freund-Levi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alzheimer s disease; progressive neurodegenerative disease; omega-3 fatty acid n-3 FA docosahexaenoic acid; DHA; eicosapentatenoic acid; EPA; linoleic acid; LA; acetylcholinesterase inhibitors; AChEI; Minimental State Examination; MMSE; ADAS-cog; Clinical Dementia Rating scale; CDR; Neuropsychiatric Inventory; NPI; Montgomery Åsberg Depression Rating scale; MADRS; Disability Assessment for Dementia; DAD; Care givers burden CGB; APOEε4; hs-CRP; IL-6; TNF-α and sIL-RII; Aβ42; T-tau and P-tau; weight; Body Mass Index; BMI.;

    Sammanfattning : Alzheimer's disease (AD) is a major public health concern in all countries with an increasing prevalence. It is expected to quadruple by the year 2047. LÄS MER

  3. 12. Intestinal dendritic cell migration and induction of T cell responses

    Författare :Karin Hägerbrand; Adaptivt immunförsvar; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The intestine represents the body’s largest surface exposed to the outer world and is thus a major entry site for pathogens such as bacteria and viruses. The intestinal immune system has the important task of protecting us against infection while maintaining tolerance against the vast amount of commensal microbes populating the intestinal tract and the multitude of foreign antigen present in the diet. LÄS MER

  4. 13. Inflammation and cell migration in chronic obstructive pulmonary disease (COPD)

    Författare :Kristin Blidberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD), the fourth most common cause of death worldwide, is characterised by chronic airflow obstruction and chronic inflammation which affects large and, especially, small airways. There is an accumulation of inflammatory cells in the airways in COPD, in particular neutrophils, macrophages and CD8+ T-cells. LÄS MER

  5. 14. Pharmacoepidemiologic studies of drug safety in pediatric chronic inflammatory disease

    Författare :Viktor Wintzell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Safety evidence for use of pharmaceutical drugs in children, including treatments for serious conditions such as chronic inflammatory diseases, is generally scarce. Off-label use is common and clinicians need to rely on evidence from adults when prescribing to children. LÄS MER

  7. 15. Effects of Th-1 and Th-2 Cytokines and Reactive Oxygen Species on Normal Human Bronchial Epithelial Cells

    Författare :Caroline Kampf; Benjamin Gaston; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; ytokines; desmosomes; focal adhesions; free radicals; hypochlorous acid; nitric oxide; normal human bronchial epithelial cells; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Epithelial damage and shedding of the epithelium are common observations in many airway diseases such as asthma, Sjögren’s syndrome, chronic obstructive pulmonary disease and cystic fibrosis. The ability of the cells to attach to each other and/or to the matrix seems to be altered. LÄS MER