Sökning: "TDT"

Visar resultat 6 - 10 av 15 avhandlingar innehållade ordet TDT.

  1. 6. Which Genes are Involved? - Statistical Planning and Analysis of Human Genetic Samples

    Författare :Staffan Nilsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis consists of six papers related to the statistical planning and analysis of human genetic samples. The first four mainly concern statistical methodology, while the last two are applied papers in genetics and medicin. In paper A an alternative method of estimating the locus specific sibling relative risk .lambda. LÄS MER

  3. 7. Pharmacological Studies of CHS 828 and Etoposide Induced Tumour Cell Death

    Författare :Petra Martinsson; Stig Linder; Uppsala universitet; []
    Nyckelord :Medical sciences; Cancer chemotherapy; cell death; caspase; etoposide; CHS 828; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; klinisk farmakologi; Clinical Pharmacology;

    Sammanfattning : Antitumour properties of the cyanoguanidine CHS 828 and analogues were discovered in 1997. CHS 828 is presently in clinical phase I/II trials. This thesis encompasses in vitro studies of the kinetics and mode of cell death induced in the human cell line U-937 GTB, by CHS 828 and the standard antitumour drug etoposide. LÄS MER

  4. 8. Multiple sclerosis linkage analysis and DNA variation in a complex trait

    Författare :Helena Modin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis is a life-long disease affecting approximately 11.000 individuals in Sweden today. It is the second most common cause of neurological disability amongst young adults, only outnumbered by traffic accidents. Genetic epidemiological studies indicate that genetic factors contribute to the susceptibility of MS. LÄS MER

  5. 9. On Test Design

    Författare :Sigrid Eldh; Hans Hansson; Sasikumar Punnekkat; Eleine Weyuker; Mälardalens högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Software Test; Test Design Techniques; Test Design; Test Automation; Test Efficiency; Computer science; Datavetenskap; Computer Science; datavetenskap;

    Sammanfattning : Testing is the dominating method for quality assurance of industrial software. Despite its importance and the vast amount of resources invested, there are surprisingly limited efforts spent on testing research, and the few industrially applicable results that emerge are rarely adopted by industry. LÄS MER

  7. 10. To be or not to be, unraveling molecular mechanisms for lineage decisions in developing blood cells

    Författare :Robert Månsson; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; common lymphoid precursor CLP ; early B-cell factor 1 EBF1 ; B-cell; Stemcell; hematopoiesis; extracellulära vätskor; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : All hematopoietic cells originate from hematopoietic stem cells (HSC) residing in the BM. The process of differentiation, through which HSCs generate progenitors and subsequently mature blood cells has been extensively studied but many of the regulatory mechanisms involved remains elusive. LÄS MER