Sökning: "Systembiologi"

Visar resultat 11 - 15 av 273 avhandlingar innehållade ordet Systembiologi.

  1. 11. Reaction-Diffusion kinetics of Protein DNA Interactions

    Författare :Anel Mahmutovic; Johan Elf; David van der Spoel; Pieter Rein ten Wolde; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; umbrella sampling; molecular dynamics; RDME; PDE; sliding; intersegment transfer; hopping; sterics; intersegment transfer; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Transcription factors need to rapidly find one specific binding site among millions of nonspecific sites on the chromosomal DNA. In this thesis I use various aspects of reaction-diffusion theory to investigate the interaction between proteins and DNA and to explain the searching, finding and binding to specific operator sites. LÄS MER

  3. 12. Improving cyanobacteria productivity: From theory to assay

    Författare :Kiyan Shabestary; Elton P. Hudson; Daniel Ducat; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; metabolic engineering; growth-coupling; growth-arrest; cyanobacteria; CRISPRi; CRISPRi library; flux balance analysis; genome-scale model; butanol; lactate; isoprene; Bioteknologi; Biotechnology;

    Sammanfattning : Bio-based production of biochemicals and biofuels holds great promises for the transition towards a more sustainable society. With increasing levels of carbon dioxide (CO2) in the atmosphere, cyanobacteria stand apart as natural catalysts directly converting CO2 and light to product. LÄS MER

  4. 13. Computational methods for calculating binding free energies of ligands in COX-1

    Författare :Yasmin Shamsudin Khan; Johan Åqvist; Jens Carlsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 14. Towards a deeper understanding of the human brain

    Författare :Evelina Sjöstedt; Mathias Uhlén; Jan Mulder; Caroline Kampf; Elly Hol; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain; organization; RNA; classification; mapping; proteins; antibodies; Bioteknologi; Biotechnology;

    Sammanfattning : Identifying the proteome variation in different parts of the body provides fundamental molecular details, enabling further findings and mapping of tissue specific proteins. By combining quantitative transcriptomics with qualitative antibody based proteomics, the Human Protein Atlas (HPA) project aims to protein profile each human protein-coding gene. LÄS MER

  7. 15. In the quest for a cold tolerant variety : gene expression profile analysis of cold stressed oat and rice

    Författare :Angelica Lindlöf; Högskolan i Skövde; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cold tolerance; oat; rice; bioinformatics analysis; Bioinformatics; Bioinformatik; Technology; Teknik; cold tolerance; oat; rice; bioinformatics analysis;

    Sammanfattning : Cold acclimation is a process which increases the freezing tolerance of an organism, after exposure to low, non-freezing temperatures. The acclimation ensures that cold tolerant species can endure harsh winter conditions, by preparing them to sub-zero temperatures. LÄS MER