Sökning: "Stromal Cells"

Visar resultat 16 - 20 av 215 avhandlingar innehållade orden Stromal Cells.

  1. 16. Phenotypic and functional analysis of the mesenchymal stromal cell compartment in the thymus

    Författare :Katarzyna Sitnik; Slemhinnans immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thymus; mesenchymal cells; retinoic acid; thymic epithelial cells;

    Sammanfattning : T cells are key cellular components of the adaptive immune system that play a critical role in our defense against pathogens and cancer but also contribute to pathology in the setting of chronic inflammation and autoimmunity. The thymus constitutes the body's major T cell production site, where bone marrow-derived progenitors migrate in a co-ordinated fashion through anatomically distinct cortical and medullary regions that are composed of epithelial and mesenchymal stromal elements. LÄS MER

  3. 17. Functions and memory features of adaptive- and innate immune cells in physiological and inflammatory settings

    Författare :Gintare Lasaviciute; Eva Sverremark-Ekström; Silke Appel; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Innate immune memory; Limosilactobacillus reuteri; dendritic cells; lymphocytes; cytokines; immunological memory; intestinal epithelial cells; chemotherapy; bone marrow; secondary lymphoid organs; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The immune system is a complex but well-regulated network which cooperates with the microbiota to maintain optimal homeostasis under physiological settings. A number of factors display the capacity to alter the immune system and thus microbiota crosstalk including host genetics, diet, environmental influences and drugs such as antibiotics or chemotherapeutic agents. LÄS MER

  4. 18. Extracellular factors for preservation and delivery of stromal cells

    Författare :Kim Olesen; Karl-Henrik Grinnemo; Andreas Tilevik; Wing Cheung Mak; Cecilia Österholm; Magnus Fagerlind; Yuji Teramura; Högskolan i Skövde; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infection Biology; Infektionsbiologi;

    Sammanfattning : Modulating the immune response after a myocardial infarction seems like an appropriate strategy for reducing myocardial fibrosis. Mesenchymal Stromal Cells are immunomodulatory and have thus gained interest, but have so far not achieved the desired clinical outcomes. LÄS MER

  5. 19. Formation of Composite Islet Grafts : A novel strategy to promote islet survival and revascularization

    Författare :Ulrika Johansson; Peetra Magnusson; Korsgren Olle; Bo Nilsson; Federico Bertuzzi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet of Langerhans; cytokines and cytokinereceptors expression; endothelial cells; mesenchymal stromal cells; transplantation; revascularization; Clinical immunology; Klinisk immunologi; cellforskning; cellforskning;

    Sammanfattning : The islets of Langerhans are small and delicate spheroid organs scattered in the pancreas responsible for insulin production. Transplantation of isolated islets is a beneficial therapy for patients with a severe form of type 1 diabetes. LÄS MER

  7. 20. Exploring the role of mesenchymal stromal cells in endometriosis

    Författare :Fawaz Abomaray; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Endometriosis is a chronic inflammatory disease where there is growth of endometrial tissue in ectopic sites, most commonly within the pelvic cavity. The major symptoms of this disease are chronic pelvic pain and infertility. LÄS MER