Sökning: "Statins"

Visar resultat 36 - 40 av 92 avhandlingar innehållade ordet Statins.

  1. 36. Common medications in the risk and prognosis of lymphoid neoplasms and epidemiology of primary CNS lymphoma

    Författare :Elsa Brånvall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lymphoid neoplasms are malignancies arising from the lymphocyte, and include lymphoma subtypes, chronic lymphocytic leukemia (CLL) and multiple myeloma (MM). It is a heterogenous group of diseases, with different molecular pathogenesis, clinical characteristics, treatments and outcome. LÄS MER

  3. 37. Non-Alcoholic Fatty Liver Disease : A clinical and histopathological study

    Författare :Mattias Ekstedt; Stergios Kechagias; Stefan Lindgren; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroenterology; Gastroenterologi;

    Sammanfattning : Fatty liver has previously often been associated with excessive alcohol consumption. During the last two decades, the interest in fatty liver occurring in non-drinkers i.e. non-alcoholic fatty liver disease (NAFLD) has increased dramatically. LÄS MER

  4. 38. Inhibition of the mevalonate pathway in C. elegans: Consequences and implications

    Författare :Parmida Ranji; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mevalonate pathway; C. elegans; atfs-1; mitochondrial unfolded response UPR ;

    Sammanfattning : The mevalonate pathway in human is responsible for the synthesis of cholesterol and other important biomolecules such as coenzyme Q (a component of the electron transport chain in mitochondria), dolichols (important for N-linked glycosylation of proteins) and isoprenoids (important for the membrane association of small GTPases). This thesis concerns novel findings about the effect of statin on the mevalonate pathway using C. LÄS MER

  5. 39. Endothelial dysfunction in patients with glucose abnormalities and coronary artery disease : studies of pathogenesis and treatment

    Författare :Magnus Settergren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Type 2 diabetes is associated with endothelial dysfunction, which is characterised by the reduced bioavailability of nitric oxide (NO). This is a result of increased oxidative stress and inflammation and the synthesis of endothelium-dependent vasoconstricting factors such as endothelin-1 (ET-1) caused by hyperglycaemia, insulin resistance and dyslipidemia. LÄS MER

  7. 40. Novel aspects of atherosclerosis : focusing on new target genes and the effect of cholesterol-lowering

    Författare :M Aránzazu Rossignoli; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is most often the main underlying cause of cardiovascular diseases (CVDs), accounting for more than 31% of all deaths worldwide. It is driven by the uptake of low-density lipoproteins (LDL) by a dysfunctional arterial endothelium. LÄS MER