Sökning: "Skin Sensitization"

Visar resultat 21 - 25 av 53 avhandlingar innehållade orden Skin Sensitization.

  1. 21. GARD - Genomic Allergen Rapid Detection. A Testing Strategy for Assessment of Chemical Sensitizers

    Författare :Henrik Johansson; Institutionen för immunteknologi; []
    Nyckelord :In vitro assay. Sensitization. Predictive genomic biomarker signature.;

    Sammanfattning : The modern world is increasingly dependent of the use of chemicals. The chemical industries have greatly contributed to the high standard of living in industrialised societies, and chemical compounds surround us in everyday life. Unfortunately, a vast number of chemicals cause adverse effects on the environment and human health. LÄS MER

  3. 22. Experimental and clinical studies on adenosine receptor stimulation in cutaneous hypersensitivity and neuropathic pain

    Författare :Karl-Fredrik Sjölund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adenosine agonists; allodynia; central sensitization; hyperalgesia; nociception; pain;

    Sammanfattning : The endogenous compound adenosine (ADO) has a wide range of physiological effects. Numerous animal studies and a limited number of human studies have shown antinociceptive effects of ADO and its analogues. The spinal cord dorsal column, where ADO receptors are found in high numbers, is a major site of action for this effect. LÄS MER

  4. 23. Exposure to birch pollen and development of atopic disease in childhood

    Författare :Anne Kihlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aeroallergens; atopy; infancy; sensitization; tolerance; antigen priming; intrauterine; maternal heredity; children; IgE; IgG; IgG4;

    Sammanfattning : Background: In 1993 extremely high levels of birch pollen were recorded in Stockholm, Sweden. This provided an opportunity to evaluate the effects of aeroallergen exposure on the early immune response. LÄS MER

  5. 24. Somatosensory dysfunctin in fibromyaligia : implications for pathophysiological mechanisms

    Författare :Eva Kosek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :allodynia; diffuse noxious inhibitory controls DNIC ; fibromyalgia; hyperesthesia; isometric contraction; pain modulation; pain inhibition; pressure algometry; quantitative sensory testing; sensitivity; sensitization; tourniquet test; v;

    Sammanfattning : Fibromyalgia is a chronic pain syndrome characterized by generalized pain, tenderness, disturbed sleep and pronounced fatigue. The pathophysiology is unknown but peripheral mechanisms (i.e., muscle ischemia) as well as central mechanisms (dysfunction in endogenous pain modulation) have been implicated. LÄS MER

  7. 25. Hairdressers : hand eczema, hair dyes and hand protection

    Författare :Marie-Louise Lind; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :hand eczema incidence; hairdresser; atopy; attributable fraction; skill exposure; permanent hair lye; aromatic amines hand rinse sampling; sampling efficiency; skin; occupational dermal exposure; protective glove; permeability hair dye compound;

    Sammanfattning : Hand eczema is a well-known problem in occupations that involve largely manual work, in combination with long periods of wet exposure and skin contact with chemicals. Hairdressing involves dermal exposure to a number of skin damaging substances. LÄS MER