Sökning: "antigen priming"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden antigen priming.

  1. 1. Maturation of humoral immune responses : Studies on the effects of antigen type, apoptosis and age

    Författare :Karin Lindroth; Carmen Fernández; Kenneth G.C. Smith; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; B cell; humoral immune response; Immunology; Immunologi;

    Sammanfattning : The humoral immune response is dependent on the formation of antibodies. Antibodies are produced by terminally differentiated B cells, plasma cells. Plasma cells are generated either directly from antigen challenged B cells, memory cells or from cells that have undergone the germinal center (GC) reaction. LÄS MER

  3. 2. Dendritic cell presentation of type II collagen

    Författare :Meirav Holmdahl; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; chromosome 2; arthritis; proteases; antigen presentation; Dendritic cell; type II collagen;

    Sammanfattning : Type II collagen (CII) is the main protein component of cartilage and immune recognition of CII plays a critical role for the development of collagen induced arthritis (CIA), a widely used animal model for rheumatoid arthritis (RA). Antigen presentation is an important requirement for the immune response, the more efficient presentation of the antigen the better tolerance will be induced and thereby protect against arthritis. LÄS MER

  4. 3. IgG3 Complements IgM in the Complement-Mediated Regulation of Immune Responses

    Författare :Lu Zhang; Birgitta Heyman; Jenny Hallgren; Frida Henningsson; Kristina Lejon; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgG3; IgM; marginal zone B cells; follicular dendritic cells; complement receptors 1 and 2; C1q; C3; antigen transport; Immunologi; Immunology;

    Sammanfattning : An intact complement system is essential for the initiation of a normal antibody response. Antibodies can regulate their own production against the antigens that they are specific for. Both IgG3 and IgM are able to enhance the antibody response via complement. LÄS MER

  5. 4. Regulation of T cell effector functions in the intestinal mucosa

    Författare :Petra Holmkvist; Slemhinnans immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T cells; memory; intestine; cytokines; differentiation; IL-18; inflammation; antigen presentation;

    Sammanfattning : T lymphocytes are a critical cellular component of the adaptive immune response. They are generated in the thymus from bone marrow derived progenitors, where they undergo commitment to the T cell lineage and differentiate and mature into naïve CD4+ and CD8+ T cells. LÄS MER

  7. 5. Innate immune responses in vivo after antigen administration : implications for vaccine development

    Författare :Frank Liang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inducing high magnitude of antibodies with epitope breadth over prolonged periods of time is likely a prerequisite to prevent several of the world’s most serious infectious diseases such as HIV-1, malaria and tuberculosis for which there are no vaccines yet. A much better understanding of the innate immune mechanisms that are critical for inducing strong responses to vaccination is therefore essential. LÄS MER