Sökning: "SLBs"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet SLBs.

  1. 1. The influence of adhesion molecules on binding and protein organization in cell contacts

    Författare :Tommy Dam; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; T cell; SLBs; Calcium Signaling; TIRF microscopy; Two-Dimensional affinity; Protein Segregation; Protein Organization; Protein Height;

    Sammanfattning : Interactions between immune cells such as T cells and antigen-presenting cells (APCs) are integral for mounting an adaptive immune response. The interaction between the T cell receptor (TCR) and the antigen-presenting major histocompatibility complex (pMHC) on a contacting T cell and APC, is widely accepted to be the key interaction. LÄS MER

  3. 2. Binding Kinetics of Proteins at Immune-Cell Contacts

    Författare :Manto Chouliara; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; T cells; Binding Kinetics; Affinity; Lifetime; CD4; CD2; TIRF Microscopy; SLBs;

    Sammanfattning : Protein-protein interactions are crucial in numerous cellular functions and biological processes that take place inside our body. It is therefore not surprising that these interactions also govern the response of our body´s defence mechanism, the so-called immune system, towards an infection. LÄS MER

  4. 3. Stimuli-responsive lipid bilayer mimics for protein, virus and cell recognition

    Författare :Sing Yee Yeung; Malmö universitet; []
    Nyckelord :Lipid bilayers; Adaptable; Self-assembled; Monolayers; Supramolecular chemistry; Cell adhesion; Biocensor;

    Sammanfattning : The most well-studied two-dimensional biomimetic cellular membrane modelsare self-assembled monolayers (SAMs) and supported lipid bilayers (SLBs).The former has the advantage of control over ligand density, homogeneity andorientation, allowing unambiguous interaction studies. LÄS MER

  5. 4. Supported Lipid Membranes and Their Use for the Characterization of Biological Nanoparticles

    Författare :Silver Jõemetsa; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence microscopy; supported lipid bilayer; lipophilic dyes; size determination; diffusion; microfluidics;

    Sammanfattning : Biological nanoparticles (BNPs) are nano-sized lipid vesicles of biological origin, which are involved in multiple biological processes. BNP characterization techniques are critical for improving the understanding of how these particles contribute to cellular communication, viral infections and drug-delivery applications. LÄS MER

  7. 5. Lipid Vesicle Fusion: Investigation, Generation and Manipulation of Cell-Membrane Mimics

    Författare :Lisa Simonsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; diffusion; spreading lipid bilayers; cell mimic; micromanipulation; lipid bilayer; microfluidics; site-specificity; DNA; membrane-receptor interactions; total internal reflection fluorescence microscopy; model system; self-assembly; TIRF microscopy; FRET; exocytosis; vesicles; fluorescence resonance energy transfer; biomembranes; amperometry; membrane fusion;

    Sammanfattning : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. In this work, cell-membrane mimics were constructed and evaluated as models for studies of the membrane-fusion process. LÄS MER