Sökning: "spreading lipid bilayers"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden spreading lipid bilayers.
1. Lipid Vesicle Fusion: Investigation, Generation and Manipulation of Cell-Membrane Mimics
Sammanfattning : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. In this work, cell-membrane mimics were constructed and evaluated as models for studies of the membrane-fusion process. LÄS MER
2. The self-spreading double bilayer/Advances in lipid membrane nanotechnology
Sammanfattning : In my thesis I describe the generation, characterization and uses of self-spreading double bilayers. This new type of solid-supported model membrane combines features and properties of the 2D lipid bilayer membrane, and the 3D phospholiposome. The double bilayer membrane, i.e. LÄS MER
3. Lipid sponge phase nanostructures as carriers for enzymes
Sammanfattning : Nonlamellar lipid liquid crystalline phases have many potential applications, such as for drug delivery, protein encapsulation or crystallization. Lipid liquid crystalline sponge phase (L3) has so far not been very much considered in these applications, in spite of apparent advantages in terms of its flexibility and capacity of forming large aqueous pores able to encapsulate large bioactive molecules. LÄS MER
4. Supported Lipid Membranes and Their Use for the Characterization of Biological Nanoparticles
Sammanfattning : Biological nanoparticles (BNPs) are nano-sized lipid vesicles of biological origin, which are involved in multiple biological processes. BNP characterization techniques are critical for improving the understanding of how these particles contribute to cellular communication, viral infections and drug-delivery applications. LÄS MER
5. Probing and elucidating the dynamics of virus-membrane interaction via plasma membrane mimics
Sammanfattning : Virus infection is initiated by the attachment of a virion to a susceptible cell’s plasma membrane, in a highly dynamic and well-orchestrated process that encompasses various steps and engages numerous viral and cellular factors. These dynamic steps may include initial non-specific binding to ubiquitous cell-membrane ligands, diffusion across the membrane to a suitable entry site and virus engagement with various receptors and co-receptors on the cell surface. LÄS MER