Sökning: "Ribosome biogenesis"

Visar resultat 6 - 10 av 43 avhandlingar innehållade orden Ribosome biogenesis.

  1. 6. The interactome of the yeast mitochondrial ribosome : Organization of mitochondrial post-transcriptional regulation, membrane protein insertion and quality control

    Författare :Braulio Vargas Möller-Hergt; Martin Ott; Michal Minczuk; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitochondrial post-transcriptional regulation; mitochondrial ribosome; membrane protein insertion; mitochondrial quality control; Biochemistry; biokemi;

    Sammanfattning : The proteins found in mitochondria originate from two different genetic systems. Most mitochondrial proteins are synthesized in the cytosol and post-translationally imported into the organelle. However, a small subset of mitochondrial proteins is encoded in an organelle-resident genome. LÄS MER

  3. 7. Transcriptional regulation of ribosome biogenesis in skeletal muscle growth

    Författare :Chang Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Resistance exercise induces skeletal muscle hypertrophy via repeated exercise bouts. The increased muscle protein synthesis together with altered muscle protein degradation contribute to the adaptation of muscle mass. The number of ribosomes dictates the protein synthetic capacity of muscle. LÄS MER

  4. 8. Factors modulating tRNA biogenesis and function in Saccharomyces cerevisiae

    Författare :Fu Xu; Anders Byström; Marcus J. O. Johansson; Raffael Schaffrath; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Translation; tRNA biogenesis; suppressor tRNA; Elongator complex; wobble uridine modifications; SUP4; YPK9; SSD1; serine tRNA; synthetic lethality; yeast; biology; biologi; molekylärbiologi; Molecular Biology; Genetics; genetik;

    Sammanfattning : Transfer RNA (tRNA) genes are transcribed by RNA polymerase III as precursors that undergo multiple processing steps to form mature tRNAs. These steps include processing of the 5’ leader and 3’ trailer sequences, addition of a 3’ CCA tail, removal of introns, and formation of modified nucleosides. LÄS MER

  5. 9. Study of the Link between Translation Termination and Ribosome Biogenesis

    Författare :Magdalena Kaczanowska; Monica Rydén Aulin; Catherine L. Squires; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Mikrobiologi;

    Sammanfattning : Release factor 1 (RF1) is a ribosome-binding protein required for termination of translation in Escherichia coli. To study the effect of slow termination on protein synthesis, two isolated suppressors to a temperature sensitive (Ts) mutant allele of RF1 were studied. LÄS MER

  7. 10. On new and current treatments for Diamond-Blackfan anemia

    Författare :Sara Sjögren; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :Diamond-Blackfan anemia; Erythropoiesis; Ribosome biogenesis; Heme synthesis; Glucocorticoids; p53; Globin translation; HRI; a1-microglobulin;

    Sammanfattning : Diamond-Blackfan anemia (DBA) is a rare congenital disease where the patients suffer from macrocytic anemia due to reduced numbers of erythroid precursors in the bone marrow. Most patients carry mutations in ribosomal proteins, such as ribosomal protein S19 (RPS19), which causes deficient ribosome biogenesis and affects protein translation. LÄS MER