Sökning: "Monica Rydén Aulin"
Hittade 4 avhandlingar innehållade orden Monica Rydén Aulin.
Sammanfattning : The aim of this thesis was to study components involved in translational termination. Most of the work is centered around this, but the outcome of some of the experiments, led me onto other paths too.Firstly, isolation of a mutant which was shown to be in release factor one, was mapped to min 26,5 on the Escherichia coli chromosome. LÄS MER
Sammanfattning : During translation termination the stop codons UAA and UAG are recognised by release factor one (RF1). RF1 binds to the ribosome and mediates the hydrolysis of the nascent peptide from the peptidyl-tRNA. In this process, RF1 interacts directly or indirectly with several ribosomal proteins (r-proteins). LÄS MER
3. Formation and function of wobble uridine modifications in transfer RNA of Saccharomyces cerevisiae
Sammanfattning : Transfer RNAs (tRNAs) act as adaptor molecules in decoding messenger RNA into protein. Frequently found in tRNAs are different modified nucleosides, which are derivatives of the four normal nucleosides, adenosine (A), guanosine (G), cytidine (C), and uridine (U). LÄS MER
Sammanfattning : Release factor 1 (RF1) is a ribosome-binding protein required for termination of translation in Escherichia coli. To study the effect of slow termination on protein synthesis, two isolated suppressors to a temperature sensitive (Ts) mutant allele of RF1 were studied. LÄS MER