Sökning: "Reproductive toxicity"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden Reproductive toxicity.

  1. 1. Toxicological studies of di-n-butyl phthalate (DBP) : Impact on the reproductive system and gut microbiota

    Författare :Radwa Almamoun; Oskar Karlsson; Paula Pierozan; Harri Alenius; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dibutyl phthalate; Antiandrogen; Gut microbiota; Reproductive toxicity; Endocrine disrupting chemicals; Environmental contaminants; Phthalates; Plastics; 3D cell culture model; Exposome; Toxicology; Environmental Sciences; miljövetenskap;

    Sammanfattning : The potential health impact of exposure to anthropogenic chemicals has raised major concerns worldwide. Phthalates are mainly used in the plastic industry and have been associated with adverse effects in humans. Di-n-butyl phthalate (DBP) is one of the dominant phthalates with a ubiquitous presence in the environment. LÄS MER

  3. 2. Copepods in Skeletonema-dominated food webs : Toxicity and nutritional quality as factors controlling copepod-diatom interactions

    Författare :Roswati Md Amin; Ulf Båmstedt; Sigrun Jónasdóttir; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Copepod-diatom interaction; toxicity; nutritional quality; Skeletonema;

    Sammanfattning : My thesis focuses on copepod-diatom interactions, specifically on the effects of food quality and toxicity on copepod feeding, reproductive success and behavior but as a frame, also includes a quantitative evaluation of copepod carbon requirements compared to other trophic plankton groups. My aim was to evaluate the function of copepods in diatom-dominated spring blooms. LÄS MER

  4. 3. The Xenopus tropicalis model for developmental endocrine and reproductive toxicity : Histological and molecular endpoints for disrupted spermatogenesis

    Författare :Sofie Svanholm; Cecilia Berg; Oskar Karlsson; Valérie Langlois; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Endocrine disrupting chemicals; Reproductive toxicology; Developmental toxicology; Spermatogenesis; Transgenerational; Xenopus tropicalis; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Sammanfattning : Endocrine disrupting chemicals (EDCs) are linked to adverse effects in both humans and wildlife. There are however, large knowledge gaps regarding cause-effect and dose-response relationships between the interference with endocrine pathways and adverse effects in the organism, especially at puberty and in subsequent generations. LÄS MER

  5. 4. Melanosome transfer, photoreception and toxicity assays in melanophores

    Författare :Daniel Hedberg; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; colour change; melanophores; melanosome; intracellular transport; pigment transfer; photoreception; toxicity assay; Roundup; glyphosate;

    Sammanfattning : Many animals such as fish and frogs have developed the ability to change colour of their skin to adapt to the environment or to signal to other individuals. This ability is due to specialised skin cells called melanophores. LÄS MER

  7. 5. The effect of intra-abdominal local anaesthetics following major gynaecological surgery. Clinical and experimental studies

    Författare :Jane M. Hayden; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Local anaesthetics; postoperative pain; hysterectomy; inflammation; ropivacaine toxicity; ovarian cancer; recovery; ovarian cancer cells;

    Sammanfattning : Background: Local anaesthetics (LA), in addition to inhibition of pain signalling, also have anti-inflammatory properties. In vitro studies have demonstrated anti-proliferative and cytotoxic effect of LAs on cancer cells when administered in therapeutic concentrations. LÄS MER