Sökning: "Post Mortem Human Subjects"

Visar resultat 6 - 10 av 17 avhandlingar innehållade orden Post Mortem Human Subjects.

  1. 6. Distribution and regulation of neuropeptide Y and its receptors in the human and rat brain : role in affective disorders

    Författare :Laura Caberlotto; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :neuropeptide Y; neuropeptide Y receptors; human; depression; Flinder Sensitive Line rats; in situ hybridization; receptor autoradiography; immunohistochemistry;

    Sammanfattning : Neuropeptide Y (NPY) is one of the most abundant peptides found within the mammalian brain. Many studies have documented that this 36-amino acid peptide exerts a wide range of central effects. LÄS MER

  3. 7. Head kinematics in car–pedestrian crashes: The influence of sliding, spine bending, elbow and shoulder impacts

    Författare :Ruth Paas; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Human Body Model; shoulder; kinematics; pedestrian; THUMS; spine; PMHS; head;

    Sammanfattning : In vehicle–pedestrian crashes, head injuries account for an overwhelming percentage of all severe and fatal injuries. These injuries are caused by the linear acceleration and rotation of the head. To mitigate head injuries, tools such as Human Body Models (HBMs) are used in the development and evaluation of pedestrian safety systems. LÄS MER

  4. 8. Neuromuscular injuries and pharyngeal dysfunction in snorers and sleep apnea patients : a study on pathological changes in the human soft palate and its relationship with swallowing dysfunction

    Författare :Farhan Shah; Per Stål; Sture Forsgren; Diana Berggren; Eva Svanborg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Axons; BDNF; desmin; dystrophin; obstructive sleep apnea; OSA; pharyngeal function; muscle; myopathy; neuropathy; Schwann cells; swallowing dysfunction; upper airway; Medical Cell Biology; medicinsk cellbiologi; oto-rhino-laryngologi; Oto-Rhino-Laryngology; patologi; Pathology; molecular cell biology; molekylär cellbiologi;

    Sammanfattning : Obstructive sleep apnea (OSA) is a prevalent progressive sleep disorder with serious negative health consequences. Although several risk factors such as obesity can make an individual vulnerable to develop OSA, the pathophysiological mechanism for the collapse of the upper airway is unclear. LÄS MER

  5. 9. Neck injuries in rear impacts : Dummy neck development, dummy evaluation and test condition specifications

    Författare :Astrid Linder; Chalmers University of Technology; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Neck; Injury; Anthropometric dummy; Severity; Impact test; Rear end collision; Seat; Mathematical model; Velocity; Thesis; Optimization; Mathematical neck models; Rear impact tests; Biomechanics; Road: Components of the vehicle; Road: Components of the vehicle;

    Sammanfattning : The objective of the work underlying this thesis was firstly to develop a neck for a new rear impact dummy, to evaluate the complete dummy and to specify test conditions for a consumer test with attention to AIS 1 neck injuries in rear impacts. In the development of the dummy neck, a mathematical neck model was developed and evaluated. LÄS MER

  7. 10. In vitro and postmortem studies of the brain opioid system : association to opiate dependence

    Författare :Parisa Zarnegar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Opioid system; brain; gene expression; amygdala; hippocampus; opiate dependence;

    Sammanfattning : Opioids such as heroin are highly addictive illicit drugs. The μ opioid receptor (MOR) plays a central role in mediating the effects of opiates and related opioid. LÄS MER