Sökning: "Pharmaceutical processes"

Visar resultat 6 - 10 av 169 avhandlingar innehållade orden Pharmaceutical processes.

  1. 6. Modelling and prediction of drug transport processes with experimental and calculated molecular properties : A multivariate approach

    Författare :Thomas Österberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : Less than 2% of the lead compounds generated by the pharmaceutical industry enter the exploratory drug-development phase, from which point they stand only a 10% chance of becoming a commercial medicine. A large proportion of the compounds fail due to poor biopharmaceutical properties, such as permeability and solubility. LÄS MER

  3. 7. Compression analysis as a tool for technical characterization and classification of pharmaceutical powders

    Författare :Josefina Nordström; Göran Alderborn; Maria Strömme; Katharina Picker-Freyer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; compaction; compression; granules; Kawakita; mechanical properties; particles; PAT; pharmaceutical powders; tablets; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : There are today strong incentives for an increased understanding of material properties and manufacturing processes to facilitate the development of new technologies in the pharmaceutical industry. The purpose of this thesis was to suggest methods requiring a low sample amount for characterization of technical properties of powders. LÄS MER

  4. 8. A Microwave Tomography Framework for Monitoring of Pharmaceutical Processes

    Författare :Livia Cerullo; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Sensitivity Analysis; Microwave Tomography; Reconstruction Algorithm; Parameterization; Pharmaceutical Processes;

    Sammanfattning : Industrial pharmaceutical processes may be very difficult to monitor and control. Today, an important research fields is non-invasive measurement techniques that provide information about thematerial distribution inside the process. In this thesis, a microwave tomography (MWT) framework for monitoring of pharmaceutical processes is presented. LÄS MER

  5. 9. Terahertz sensing for pharmaceutical applications

    Författare :Anis Moradikouchi; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; frequency domain spectroscopy; terahertz sensing; multivariate analysis; Pharmaceutical; radar; porosity; powders; API content; tablets; powder flow characterization; tablet density;

    Sammanfattning : Pharmaceutical tablets are manufactured through the compaction of powder blends or granules in batch or continuous processes. In continuous manufacturing, real-time assurance of quality becomes essential to ensure that the final product meets the quality standards approved by manufacturers and regulatory authorities. LÄS MER

  7. 10. Microwave Measurement Systems for In-line 3D Monitoring of Pharmaceutical Processes

    Författare :Livia Cerullo; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; permittivity; moisture content; microcrystalline cellulose; Pharmaceutical processes; dispersive media; finite element method; microwave measurements;

    Sammanfattning : The monitoring and understanding of pharmaceutical processes are important in order to achieve high-quality products at a low-production cost. The presence of water, e.g. as moisture content in the solid-state pharmaceutical material, is ofparticular interest and importance. LÄS MER