Sökning: "Josefina Nordström"

Hittade 2 avhandlingar innehållade orden Josefina Nordström.

1. 1. Compression analysis as a tool for technical characterization and classification of pharmaceutical powders

   Författare :Josefina Nordström; Göran Alderborn; Maria Strömme; Katharina Picker-Freyer; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; compaction; compression; granules; Kawakita; mechanical properties; particles; PAT; pharmaceutical powders; tablets; Pharmaceutics; Galenisk farmaci;

   Sammanfattning : There are today strong incentives for an increased understanding of material properties and manufacturing processes to facilitate the development of new technologies in the pharmaceutical industry. The purpose of this thesis was to suggest methods requiring a low sample amount for characterization of technical properties of powders. LÄS MER

3. 2. Tableting performance of dry granulated particles : Significance and assessment of compression mechanical properties

   Författare :Maryam Tofiq; Göran Alderborn; Ann-Sofie Persson; Josefina Nordström; Peter Kleinebudde; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dry granulation; Powder compression; Compression parameters; Granule composition; Granule structure; Granule strength; Granule fragmentation; Granule deformation; Tablet tensile strength; Loss of tabletability;

   Sammanfattning : Dry granulation (DG) is often utilized as an intermediate process during tablet manufacturing, for improving flow characteristics of the powder blend and/or reducing segregation issues related to the active pharmaceutical ingredient (API). The resulting granules exhibit typically irregular shapes with rough surfaces and their mechanical properties are related to the feeding powder and the process parameters used during the DG. LÄS MER