Sökning: "Peptide receptor"
Visar resultat 26 - 30 av 505 avhandlingar innehållade orden Peptide receptor.
26. Mutational analysis of melanocortin receptors 1 and 5
Sammanfattning : The melanocortin receptor family includes five subtypes, named MC1R to MC5R. Melanocortin receptors are predominantly coupled to second messenger pathway of cyclic AMP through coupling to G-protein. This study is focused on structure-function relationship of MC1R and MC5R. LÄS MER
27. Theranostics in Neuroendocrine Tumors : Somatostatin Receptor Imaging and Therapy
Sammanfattning : Neuroendocrine tumors (NETs) are characterized by cellular overexpression of somatostatin receptors (SSTR), which allows for the use of radiolabeled somatostatin analogs (SSA) for both imaging and therapy. Because NETs often are diagnosed at a metastatic stage, curative surgery is not possible. LÄS MER
28. Human papillomavirus tropism : determinants of viral tissue specificity
Sammanfattning : Cervical cancer is the second most common cancer among women worldwide and human papillomavirus (HPV) is a prerequisit for the development of this cancer. HPV belongs to the Papillomaviridae family and infects the basal layer of epithelial cells where it generally progresses into warts or condylomas. LÄS MER
29. lmprovement of 177Lu-octreotate treatment of small-intestine neuroendocrine tumors by hyperfractionation
Sammanfattning : Neuroendocrine tumor incidence is steadily rising, and the late diagnosis often results in metastatic disease and current treatments mostly prolong life and in-crease quality of life without increasing cure rate. 177Lu-octreotate was recently approved for treatment of neuroendocrine tumors, but the dosage scheme should be optimized. LÄS MER
30. Design and Synthesis of Novel AT2 Receptor Ligands : From Peptides to Drug-Like Molecules
Sammanfattning : Many peptide receptors are of pharmaceutical interest and there is thus a need for new ligands for such receptors. Unfortunately, peptides are not suitable as orally administrated drugs since they are associated with poor absorption, rapid metabolism and low sub-receptor selectivity. LÄS MER