Sökning: "Ovarian carcinoma"

Visar resultat 21 - 25 av 44 avhandlingar innehållade orden Ovarian carcinoma.

  1. 21. The HER2/neu oncoprotein and dendritic cells in immunity against tumors

    Författare :Yang Rongcun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HER2 neu; dendritic cells; ovarian carcinoma; apoptosis;

    Sammanfattning : It is now well established that small peptide epitopes bound to the major histocompatibility complex (MHC), derived from processed proteins synthesized by the tumor cells, can be recognized as antigens by cytotoxic T lymphocytes (CTLs). A number of tumor antigens recognized by CTLs on human melanomas have been defined, but less is known about antigens from other tumor types. LÄS MER

  3. 22. Studies of T cells in health and disease : receptor usage and cytokine expression

    Författare :Eva Halapi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :T cell receptor; oligoclonal expansion Tumour-infiltrating Iymphocyte; Ovarian carcinoma; Interleukin 10; Multiple Myeloma; Systemic vasculitis; HLD DR0401*CDR3; HIV-I;

    Sammanfattning : T Iymphocytes are crucial components for the initiation and maintenance of an immune response. To identify and characterize different T cells and their antigen specific receptors has important bearing for the understanding of underlying mechanisms in immunopathological processes and also to allow for the design of therapeutic therapies to be used for modulation of immune responses. LÄS MER

  4. 23. Genomic instability and tumor progression : a cytochemical, molecular biological and cytogenetic study of human tissue from uterine cervix, colon, breast and ovary

    Författare :Harald Blegen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervical; colorectal; breast; ovarian neoplasia; proliferation; DNA ploidy; cyclins; P53; CGH;

    Sammanfattning : Disruption of cell cycle checkpoint control is believed to be common in human carcinomas. To elucidate how cell cycle defects and genomic instability cooperate we investigated the pathogenesis of carcinomas by using four different models of tumor progression in human tissue samples i.e. from the uterine cervix, colon, breast and ovary. LÄS MER

  5. 24. The role of HLA-A*02 and biomarkers in solid malignant tumours

    Författare :Emilia Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : HLA-A*02 genotype generates significantly worse outcome in patients with metastatic serous ovarian cancer and malignant melanoma. HLA-A*02 is common in the Swedish population (about 60 %), but has decreasing frequency in European countries further south. LÄS MER

  7. 25. ASNA1 and cisplatin resistance : studies in C. elegans and in human tumor cells

    Författare :Oskar Hemmingsson; Peter Naredi; Mef Nilbert; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ASNA1; Cisplatin; C. elegans; Drug resistance; Apoptosis; Surgery; Kirurgi; Oncology; Onkologi; Surgery; kirurgi; Oncology; onkologi; cellforskning; cell research;

    Sammanfattning : Platinum based chemotherapy is widely used to treat cancer. Cisplatin (diamminedichloroplatinum) combination treatments provide cure for metastatic testicular cancer and prolong survival for patients suffering from ovarian, head and neck, bladder and non small cell lung cancer. LÄS MER