Sökning: "DNA ploidy"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden DNA ploidy.

1. 1. DNA ploidy, proliferation markers and prognosis in malignant melanoma

   Författare :Margareta Karlsson; Christer Lindholm; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Malignant melanoma is a serious disease when metastases occur. It is therefore important to investigate possible tools for prediction to the outcome of the disease. In the present investigation 265 patients with cutaneous malignant melanoma and uveal melanoma was investigated with flow cytometry. LÄS MER

3. 2. Heterogeneity and biopsy strategies in prostate cancer

   Författare :Lars Egevad; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Prostate cancer; core biopsy; tumor. volume; computer simulation; DNA ploidy; tumor heterogeneity; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : For the diagnosis of prostate cancer, there is a need to develop biopsy strategies, that give representative information both for detection of cancer and for assessment of prognostic indicators.In 80 men, transrectal core biopsies from 10 standardized positions were taken before radical prostatectomy. LÄS MER

4. 3. Prognostic factors in prostate cancer with special reference to the effect of hormonal therapy

   Författare :Göran Ahlgren; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; neuroendocrine differentiation; tumour cell proliferation; DNA-ploidy; prostate cancer; prognostic factors; nephrology; Urologi; nefrologi;

   Sammanfattning : We have used image cell analysis to analyse nuclear DNA content on fine needle aspiration biopsies from 96 patients diagnosed to have prostate cancer 1980-81. By stratifying diploid and tetraploid tumours according to a cytometric proliferation index (PI), we suggest a new DNA-classification that is prognostic of death from prostate cancer in multivariate analysis including conventional prognostic factors. LÄS MER

5. 4. Prognostic Factors in Early Stages (FIGO I-II) of Epithelial Ovarian Carcinoma

   Författare :Ingirídur Skírnisdóttir; Seija Grenman; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Ovarian cancer; early stages; adjuvant therapy; prognosis; tumor grade; apoptotic regulators; p53; bcl-2; bax; growth factor receptors; HER-2 neu; EGFR; DNA ploidy; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

   Sammanfattning : From January, 1988, to December, 1993, 113 patients with FIGO stage IA-IIC epithelial ovarian carcinoma were treated with postoperative radiotherapy. The median follow-up period was 74 months. Tumor recurrences were recorded in 33 cases (30%). The cancer-specific survival rate was 72%. LÄS MER

7. 5. Long-term survival and prognostic factors in endometrial cancer - a populationbased cohort study

   Författare :Teresia Svanvik; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; relative survival; DNA ploidy; s-phase fraction; p53; socioeconomic inequality; early detection;

   Sammanfattning : Aims: The over-all aims of this thesis were to evaluate the associations between prognostic factors and excess mortality rate, between socioeconomic and immigrant status and incidence rate, in endometrioid (EEC) and non-endometrioid (NEC) endometrial carcinoma. Material and methods: Study I-III were retrospective population-based cohort studies including women resident in a defined geographical area, with endometrial carcinoma. LÄS MER