Sökning: "Oligosaccharides"

Visar resultat 16 - 20 av 137 avhandlingar innehållade ordet Oligosaccharides.

  1. 16. Early-life gut microbiota and breast milk oligosaccharides in relation to childhood immune maturation and allergy

    Författare :Ylva Margareta Sjögren; Eva Sverremark-Ekström; Outi Vaarala; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; allergy; infant; gut microbiota; human milk oligosaccharides; Bifidobacterium; Lactobacillus; Bacteroides fragilis; Clostridium difficile; family size; secretory IgA; toll like receptor; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Atopic allergy is the most common chronic disease among children in the developed world. This high prevalence could be associated with low microbial exposure. The early gut microbiota appears to be important for immune maturation. LÄS MER

  3. 17. Three-dimensional structure of oligosaccharides from molecular dynamics simulations

    Författare :Christer Höög; Lennart Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : This thesis focuses on the conformation and flexibility of oligosaccharides around the glycosidic linkage. The methods employed for the elucidation of the three-dimensional structures of biomolecules are briefly described. The main techniques used here are computer simulations and molecular dynamics simulations in aqueous solution in particular. LÄS MER

  4. 18. Synthesis of Oligosaccharides for Interaction Studies with Various Lectins

    Författare :Emiliano Gemma; Stefan Oscarson; Martina Lahmann; Hans Kamerling; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : In this thesis, the syntheses of oligosaccharides for interaction studies with various lectins are described. The first section reports the syntheses of tetra, tri- and disaccharides corresponding to truncated versions of the glucosylated arm of Glc1Man9(GlcNAc)2, found in the biosynthesis of N-glycans. LÄS MER

  5. 19. Synthesis of oligosaccharides and conformational analysis by NMR spectroscopy

    Författare :Jerk Rönnols; Göran Widmalm; Eszter Borbas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : The first part of this thesis describes investigations of the conformations of six N-linked pseudodisaccharides (Paper I), which were synthesized as glycosidase inhibitor candidates, and 10 β-D-xylopyranoside derivatives bearing hydrophobic aglycons (Paper II), by NMR spectroscopic methods. In paper I the ring conformations of 2- and 3-amino-α-D-altropyranosides, and ω torsions of altrosides, glucosides and mannosides were described, in neutral and protonated states. LÄS MER

  7. 20. Synthesis of oligosaccharides containing deoxy functions and uronic acids

    Författare :Pär Svahnberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER