Sökning: "Stefan Oscarson"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Stefan Oscarson.

1. 1. Synthesis of some oligosaccharides with D-galacto- and D-gluco-configuration and reductive opening of carbo-hydrate acetals

   Författare :Stefan Oscarson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Syntheses of the following oligosaccharides, required for immunological studies. are discussed: £-trifluoroacetamidophenyl O-a-D-glucopyranosyl-(1+4)-a-D-galactopyranoside, ß-trifluoroacetamidophenyl O-a-D-glucopyranosyl-(1 + 6)-a-D-galactopyranoside, 8-methoxy- carbonyloct-1-yl 0-a-D-galactopyranosyl-(1+3)-fi-ß~9"9alact°Pyranosyl- (1+4)-2-acetamido-2-deoxy-ß-D-glucopyranoside, methyl û-a-D-fuco- pyranosyl-(1+4)-ß-D-galactopyranoside, methyl û-a-D-galactopyranosyl- (1+4)-ß-D-fucopyranoside and methyl ß-a-D-fucopyranosyl-(1+4)-ß-D- fucopyranoside. LÄS MER

3. 2. Synthesis of Oligosaccharides for Interaction Studies with Various Lectins

   Författare :Emiliano Gemma; Stefan Oscarson; Martina Lahmann; Hans Kamerling; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

   Sammanfattning : In this thesis, the syntheses of oligosaccharides for interaction studies with various lectins are described. The first section reports the syntheses of tetra, tri- and disaccharides corresponding to truncated versions of the glucosylated arm of Glc1Man9(GlcNAc)2, found in the biosynthesis of N-glycans. LÄS MER

4. 3. Design and Synthesis of Sialic Acid Conjugates as Inhibitors of EKC-causing Adenoviruses

   Författare :Susanne Johansson; Jan Kihlberg; Mikael Elofsson; Stefan Oscarson; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sialic acid; sialylmimetics; sialylation; multivalency; glycoconjugates; adenovirus; antiviral agents; epidemic keratoconjunctivitis; Bioorganic chemistry; Bioorganisk kemi;

   Sammanfattning : The combat against viral diseases has been, and still is, a major challenge in the field of drug development. Viruses are intracellular parasites that use the host cell ma-chinery for their replication and release. Therefore it is difficult to target and destroy the viral particle without disturbing the essential functions of the host cell. LÄS MER

5. 4. Catalytic Oxidation Methods. Use of inexpensive and environmentally friendly Oxidants in organic Synthesis

   Författare :Erik Karlsson; Jan-Erling Bäckvall; Björn Åkermark; Stefan Oscarson; Kálmán Szabó; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

   Sammanfattning : .... LÄS MER

7. 5. Synthesis of Oligosaccharides from the Inner Core Structure of Haemophilus Influenzae and Neisseria meningitidis Lipopolysaccharides

   Författare :Karin Mannerstedt; Stefan Oscarson; Paul Murphy; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbohydrate; synthesis; Haemophilus influenzae; Neisseria meningitidis; Organic chemistry; Organisk kemi;

   Sammanfattning : This thesis describes the synthesis of oligosaccharides corresponding to different parts of the lipopolysaccharide (LPS) inner core structure from Haemophilus influenzae and Neisseria meningitidis. Chapter 2 describes the synthesis of a protected trisaccharide common to H. influenzae and N. LÄS MER