Sökning: "Molekylär biofysik"

Visar resultat 16 - 20 av 75 avhandlingar innehållade orden Molekylär biofysik.

  1. 16. NMR studies of host-pathogen interactions

    Författare :Katja Petzold; Jürgen Schleucher; Torleif Härd; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR; regulatory RNA; HBV; H.pylori; phospholipids; ROESY; Molecular biophysics; Molekylär biofysik; biokemi; Biochemistry;

    Sammanfattning : This thesis describes the use of Nuclear Magnetic Resonance (NMR) for characterizing two host-pathogen interactions: The behavior of a regulatory RNA of the Hepatitis B virus (HBV) and the attachment of Helicobacter pylori (H. pylori) to the gastric mucosa. LÄS MER

  2. 17. Microfluidics and AI for single-cell microbiology

    Författare :Praneeth Karempudi; Johan Elf; Yoav Shechtman; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Microfluidics; Artificial intelligence; Deep learning; Single-cell microbiology; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Most of the biological sciences deal with understanding the relationships between phenotypes and the underlying molecular mechanisms of organisms. This thesis is an engineering, computational, and experimental exercise in expanding the scope and scale of phenotype-genotype mapping techniques in single-cell microbiology using microscopy, microfluidics, and image processing. LÄS MER

  3. 18. New Roads for an Ancient Enzyme : Whole-Cell Studies and New Cofactors for [FeFe] Hydrogenases

    Författare :Marco Lorenzi; Gustav Berggren; Hannah Shafaat; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; [FeFe] hydrogenases; hydrogen; catalysis; photocatalysis; spectroscopy; whole-cell; semi-artificial enzymes; Chemistry with specialization in Molecular Biomimetics; Kemi med inriktning mot molekylär biomimetik;

    Sammanfattning : [FeFe] hydrogenases rare Nature’s best H2-processing catalysts, and one of the best candidates to satisfy societal need for cheap and efficient catalyst for H2-evolution. These enzymes owe their remarkable catalytic activities to their organometallic active site, called “H-cluster”. LÄS MER

  4. 19. Interaction of Ultrashort X-ray Pulses with Material

    Författare :Magnus Bergh; Janos Hajdu; Andrea Cavalleri; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; free-electron laser; dense plasma; X-ray; radiation damage; laser physics; nano-plasma; Molecular Dynamics; Molecular biophysics; Molekylär biofysik;

    Sammanfattning : Radiation damage limits the resolution in imaging experiments. Damage is caused by energy deposited into the sample during exposure. Ultrashort and extremely bright X-ray pulses from free-electron lasers (FELs) offer the possibility to outrun key damage processes, and temporarily improve radiation tolerance. LÄS MER

  5. 20. Crystallography in Four Dimensions : Methods and Applications

    Författare :Gunilla Carlsson; Janos Hajdu; Dieter Oesterhelt; Vilmos Fülöp; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; horseradish peroxidase; redox reactions; X-ray crystallography; haem catalysis; molecular movies; radiation damage; Molekylär biofysik; Molecular biophysics; Molekylär biofysik;

    Sammanfattning : The four-electron reduction of dioxygen to water is the most exothermic non-photochemical reaction available to biology. A detailed molecular description of this reaction is needed to understand oxygen-based redox processes. Horseradish peroxidase (HRP) is a haem-containing redox enzyme capable of catalysing the reduction of dioxygen to water. LÄS MER