Sökning: "Michael Risk"

Visar resultat 6 - 10 av 120 avhandlingar innehållade orden Michael Risk.

1. 6. The Complex Genetics behind Neurodegeneration and Susceptibility to Parkinson’s disease

   Författare :Michael Jewett; Translationell Neurogenetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s Disease; α-synuclein; Dopaminergic Neurons; Susceptibility; GSTA4; Vra1; rAAV; 6-OHDA; En1; Linkage analysis; Congenic strains; Axonal swellings; QTL; Risk factors; Neuroprotection; Astrocytes;

   Sammanfattning : Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects over 1% of people above the age of 65. This progressive and debilitating disease is usually thought of as a motor disease, with symptoms such as muscle rigidity, slowness of movement, and tremor at rest. LÄS MER

3. 7. Environmental intolerance : psychological risk and health factors

   Författare :Eva Palmquist; Steven Nordin; Gregory Neely; Berndt Stenberg; Michael Witthöft; Umeå universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Environmental intolerance; stress; anxiety; depression; burnout; prognosis; recovery; spreading; coping; social support; co-prevalence; Västerbotten Environmental Health Study; idiopathic environmental intolerance; multiple chemical sensitivity; sick building syndrome; noise sensitivity; electromagnetic hypersensitivity; Psychology; psykologi; Epidemiology; epidemiologi;

   Sammanfattning : Environmental intolerance (EI) is an embracing term for a number of conditions characterized by a wide range of non-specific symptoms attributed to certain environmental exposures (e.g. pungent/odorous chemicals, residing in a certain building, electromagnetic fields and everyday sounds). EI often leads to lifestyle alterations (e. LÄS MER

4. 8. Insights into the relationship between coronary calcification and atherosclerosis risk factors

   Författare :Rachel Nicoll; Michael Henein; Gunilla Olivecrona; Jan Engvall; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary artery calcification; risk factors; atherosclerosis; stenosis; Cardiology; kardiologi;

   Sammanfattning : Introduction Coronary artery disease (CAD) is the most common cause of death in Europe and North America and early detection of atherosclerosis is a clinical priority. Diagnosis of CAD remains conventional angiography, although recent technology has introduced non-invasive imaging of coronary arteries using computed tomographic coronary angiography (CTCA), which enables the detection and quantification of coronary artery calcification (CAC). LÄS MER

5. 9. Metabolic risk markers and relative survival in patients with aortic stenosis requiring surgery

   Författare :Anders Holmgren; Ulf Näslund; Stefan Söderberg; Michael Henein; Rune Haaverstad; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aortic stenosis; aortic valve surgery; coronary artery disease; prospective cohort study; risk markers; lipoprotein a ; apolipoproteins; proteomics; troponin T; C-reactive protein; relative survival; observed survival; kardiologi; Cardiology;

   Sammanfattning : Background: Aortic stenosis (AS) is the most common valve disorder requiring surgery in developed countries. The etiology of AS is only partly known.  Identification of new biomarkers in prospective studies could lead to novel insights in the etiology of AS, and possibly lead to improved clinical management. LÄS MER

7. 10. DNA methylation and hypomethylating agents in high-risk myelodysplastic syndromes and acute myeloid leukemia

   Författare :Michael Grövdal; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Epigenetic alterations are common in cancer. One example is aberrant hypermethylation of the promoters of tumor suppressor genes and hence silencing of gene expression. LÄS MER