Sökning: "Metabolic activation"
Visar resultat 6 - 10 av 246 avhandlingar innehållade orden Metabolic activation.
6. Modulation of the calcium-force relationship in smooth muscle by polyamines and metabolic inhibition
Sammanfattning : The relationship between intracellular free calcium ([Ca2+]i) and force in smooth muscle was investigated in receptor-coupled permeabilized preparations and by fluorimetry of the calcium indicator Fura 2 in intact smooth muscle. The time integral of spontaneous [Ca2+]i transients in the intact rat portal vein was decreased by cyanide and, during tonic contraction, cyanide reduced force without changing [Ca2+]i implying metabolic sensitivity of both membrane excitation and [Ca2+]i - activation of the contractile proteins. LÄS MER
Sammanfattning : Very long-chain fatty acids (VLCFAs), including polyunsaturated fatty acids (PUFAs), are essential lipids whose functional diversity is made possible by variation in their chain length and degree of unsaturation. Fatty acids can either be derived directly from the diet or they can be synthesized de novo through lipogenesis, up to 16 carbons in length by fatty acid synthase. LÄS MER
Sammanfattning : The nuclear receptors (NRs) constitute a highly conserved superfamily of transcription factors restricted to metazoans. In general, these receptors are regulated by small lipophilic molecules such as steroids, thyroid hormones and retinoids and play an important role in cellular regulation. LÄS MER
Sammanfattning : Retinoids (vitamin A derivatives) are essential for a wide variety of physiological processes, including embryonic development, growth, vision, reproduction, and maintenance of various epithelia and the immune system. 11-Cis-retinal serves as the chromophore of the visual pigments in the retina, whereas the hormonal retinoids, all-trans and 9-cis retinoic acid (RA), regulate the non-visual functions via activation of nuclear retinoid receptors (RARs and RXRs). LÄS MER
10. Metabolic regulation of nitrogenase in Rhodospirillum rubrum : studies on DRAG and DRAT, the regulatory proteins of dinitrogenase reductase
Sammanfattning : Nitrogen fixation is catalyzed by nitrogenase, in an ATP-dependent reaction where dinitrogen is reduced to ammonium. Nitrogenase is a protein complex consisting of two proteins; dinitrogenase and dinitrogenase reductase and the reaction is only carried out by prokaryotes. LÄS MER