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1. 1. Hyperthermia-responsive liposomal systems

   Författare :Yujia Jing; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cationic lipid; asymmetry; phospholipase; liposomes; flip-flop; hyperthermia; phase transition; supported lipid membranes; drug delivery;

   Sammanfattning : Abstract Sophisticated liposomal systems are emerging at an increasing rate to meet the demands for multifunctional drug carriers in chemotherapies in combined with hyperthermia. For example, liposomal drug carriers for temperature-controlled drug release under hyperthermic conditions have recently been tested in clinical trials. LÄS MER

3. 2. Microfluidic Compartmentalization for Smart Materials, Medical Diagnostics and Cell Therapy

   Författare :Emre Iseri; Wouter van der Wijngaart; Nicole Pamme; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microfluidics; microfabrication; compartmentalization; partitioning; droplet microfluidics; self-assembly; 3D microarrays; soft composites; beads; particles; core-shell particle; point-of-care; diagnostics; dipstick; digital bioassays; lab-on-a-chip; urinary tract infection; bacteria detection; E. coli; cell encapsulation; hydrogel; cell therapy; spider silk; magnetic metamaterials.; Mikrofluidik; mikrotillverkning; kompartmentalisering; partitionering; droppmikrofluidik; självmontering; 3D-mikromatriser; mjuka kompositer; pärlor; partiklar; kärna-skalpartikel; vårdpunkt; diagnostik; mätsticka; digitala bioanalyser; laboration-a-chip; urinvägsinfektion; bakteriedetektering; E. coli; cellinkapsling; hydrogel; cellterapi; spindelsilke; magnetiska metamaterial.;

   Sammanfattning : The organisation of fluids in small compartments is ubiquitous in nature, such as in the cellular composition of all life. This work explores several engineering avenues where microscale fluid compartmentalization can bring novel material properties or novel functionality in life sciences or medicine. LÄS MER

4. 3. Biofabrication, Biomechanics and Biocompatibility of Nanocellulose-based Scaffolds for Auricular Cartilage Regeneration

   Författare :Hector Martinez Avila; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Nasoseptal Chondrocytes; Tissue Engineering; Auricular Cartilage; Auricular reconstruction; Bacterial Nanocellulose; Neocartilage; Nanofibrillated Cellulose; Mononuclear Cells; 3D Bioprinting;

   Sammanfattning : In about 2:10,000 births the external part of the ear, the auricle, is severely malformed or absent. Furthermore, tumors and trauma can cause defects to the auricle. LÄS MER

5. 4. Synthesis of xyloglucan oligo- and polysaccharides with glycosynthase technology

   Författare :Fredrika Gullfot; Harry Brumer; Tuula Teeri; Jerry Ståhlberg; Mats Martinelle; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glycosynthase; xyloglucan; xyloglucan endo-transglycosylase; retaining glycoside hydrolase; xyloglucanase; polysaccharide synthesis; Bioengineering; Bioteknik; Enzyme engineering; Enzymteknik; Bioorganical synthesis; Bioorganisk syntes; Biomaterials; Biomaterial;

   Sammanfattning : Xyloglucans are polysaccharides found as storage polymers in seeds and tubers, and as cross-linking glycans in the cell wall of plants. Their structure is complex with intricate branching patterns, which contribute to the physical properties of the polysaccharide including its binding to and interaction with other glycans such as cellulose. LÄS MER

7. 5. Extracellular Matrix Based Materials for Tissue Engineering

   Författare :Cecilia Aulin; Jöns Hilborn; Tim Bowden; Laura Creemers; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Extracellular matrix; collagen synthesis; bioreactor; cell culture; bone morphogenetic protein-2; noggin; hyaluronan; cartilage; Medical technology; Medicinsk teknik; Molecular biology; Molekylärbiologi; Orthopaedics; Ortopedi; Transplantation surgery; Transplantationskirurgi; Biomaterials; Biomaterial; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Cell and molecular biology; Cell- och molekylärbiologi; Polymer chemistry; Polymerkemi; Materials chemistry; Materialkemi; cellforskning; Cell Research; materialvetenskap; Materials Science; medicinsk cellbiologi; Medical Cell Biology; ortopedi; Orthopaedics;

   Sammanfattning : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. LÄS MER