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Visar resultat 6 - 10 av 13 avhandlingar som matchar ovanstående sökkriterier.

  1. 6. Biomarkers and surgical predictors in temporomandibular joint disease

    Författare :Mattias Ulmner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Temporomandibular joint (TMJ) disc displacement (DD) is associated with pain and impaired function and has two main sub-diagnoses, DD with or without reduction (DDwR/DDwoR). DD synovial tissue has been sparsely investigated, and further characterisation is needed. LÄS MER

  3. 7. Biomarkers in Cardiovascular Dysautonomia: an Emerging Field

    Författare :Madeleine Johansson; Kardiovaskulär forskning - hypertoni; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; Cardiovascular autonomic dysfunction; Syncope; Orthostatic hypotension; Postural Orthostatic Tachycardia Syndrome; Cardiovascular disease; Autonomic dysfunction;

    Sammanfattning : Background: Cardiovascular autonomic dysfunction is a multifactorial disorder manifested as orthostatic hypotension (OH) and postural orthostatic tachycardia syndrome (POTS). OH has been associated with an increased risk of cardiovascular disease (CVD), and the underlying mechanisms are not fully understood and explored. LÄS MER

  4. 8. Crosstalk between colorectal cancer cells and tumour-associated macrophages

    Författare :Yuan Zhang; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD47; tumour-associated macrophage; matrix metalloproteinase; cell migration; colon cancer;

    Sammanfattning : Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. LÄS MER

  5. 9. Translational studies of syndecan-1 as angiogenesis inhibitor : from basic research to clinical applications

    Författare :Joman Javadi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malignant mesothelioma (MM) is a highly aggressive primary tumor of the pleura, associated with poor prognosis. MM is mainly related to exposure to mineral fibers such as asbestos. The diagnosis of MM, despite multiple diagnostic tools, is challenging and treatment options are limited. LÄS MER

  7. 10. Molecular mechanisms and immunomodulatory approaches in acute cystitis

    Författare :Daniel Butler; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary tract infection; acute cystitis; Immunomodulation; IL-1beta; hyper inflammatory disorder; neurokinins;

    Sammanfattning : hand in the fight against resistant microbes. This thesis discusses the feasibility and potential of specific immunotherapy in treating acute bacterial infections and chronic sequels. The infection model is acute cystitis; the most common form of urinary tract infection, affecting millions of patients annually. LÄS MER