Sökning: "MHC"

Visar resultat 36 - 40 av 375 avhandlingar innehållade ordet MHC.

  1. 36. Natural killer cell tolerance : influence of the MHC class I expression in the host

    Författare :Maria H Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; MHC class 1; tolerance; transgenic mice; Ly49;

    Sammanfattning : Development of self-tolerance in the immune system is characterized by somatic processes aiming at permanently eliminating, or silencing, potentially autoreactive lymphocytes. Such tolerance mechanisms are of outmost importance if autoimmunity is to be avoided. LÄS MER

  3. 37. MHC and Transgenic Mice. A study into polymorphism and function of class I and class II molecules

    Författare :Mikael Vestberg; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MHC rat mouse transgenic autoimmunity collagen peptide; Clinical biology; Klinisk biologi;

    Sammanfattning : Transplantation antigens encoded in the major histocompatibility complex (MHC) bind peptides and present them to T cells. We showed that mouse T cells expressing transgenic human CD8 can recognise human MHC class I. LÄS MER

  4. 38. MHC class I molecules in natural killer cell education and tolerance

    Författare :Petter Brodin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The immune system needs to respond to danger but remain tolerant to normal cells and tissues. Natural killer cells achieve tolerance to self by the use of inhibitory receptors recognizing MHC class I molecules on healthy cells. LÄS MER

  5. 39. Binding and immunogenicity of MHC class-I specific peptides and glycopeptides

    Författare :Ussama M Abdel-Motal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Short synthetic MHC class I (MHC-I) Db and Kb binding peptides were found to be strongly immunogenic and capable of inducing virus-specific cytotoxic T lymphocyte (CTL) responses. Restimulation of primed splenocytes with a low peptide concentration generated optimal CTL responses. LÄS MER

  7. 40. Immunoecology of the Great Snipe (Gallinago media) : Mate Choice, MHC Variation, and Humoral Immunocompetence in a Lekking Bird

    Författare :Robert Ekblom; Jacob Höglund; Mats Grahn; Scott V. Edwards; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Behaviour; Major histocompatibility complex class II B; Sexual selection; Evolution; Leks; Biologi; Biology; Biologi;

    Sammanfattning : At the centre of the vertebrate immune system is a group of proteins called MHC (major histocompatibility complex) molecules. These function in self – non self recognition and activation of the immune defence against intruding parasites and pathogens. LÄS MER