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Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Pituitary Tumor Surgery - factors influencing outcome

   Författare :Tobias Hallén; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endoscopic transsphenoidal surgery; biomarkers; glial fibrillary acidic protein; neurofilaments; tau protein; pituitary tumors; sinonasal health; tumor progression; predictive markers; MCM7; methylation patterns; NFPA;

   Sammanfattning : Background: Pituitary tumors represent 15–20% of intracranial tumors. The majority are benign adenomas, of which 30 % are hormonally inactive, the non-functioning pituitary adenomas (NFPAs). LÄS MER

3. 2. The role of cyclin E in cell cycle regulation and genomic instability

   Författare :Susanna Ekholm-Reed; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cyclin E; cell cycle; Restriction point; pre-RC; Mcm proteins; DNA replication; tumorigenesis; proteolysis; hCdc4;

   Sammanfattning : Cyclin E, a positive regulatory subunit of Cdk2, normally accumulates periodically at the G1/S transition, where it promotes entry into S phase and other DNA replication-associated functions. However, in many types of human cancer, cyclin E is overexpressed and in some cases its expression becomes deregulated, a phenomenon generally associated with poor prognosis. LÄS MER