Sökning: "tumor progression"
Visar resultat 1 - 5 av 490 avhandlingar innehållade orden tumor progression.
1. Genetic Analyses of Tumor Progression in Colorectal Cancer
Sammanfattning : Colorectal tumors are responsible for more than 600 000 deaths per year worldwide and thereby constitute the second most common cause of cancer related mortality. Early detection is related to improved prognosis and identification of genetic biomarkers would meliorate available diagnostic tools. LÄS MER
2. Platelets – Multifaceted players in tumor progression and vascular function
Sammanfattning : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. LÄS MER
3. Cyclooxygenase activity and tumor progression
Sammanfattning : Invasive growth of malignant tumors is associated with local and systemic inflammation, which may promote progression and metastases. Inflammation is also responsible for appearing manifestations of advanced cancer as fatigue, anorexia and wasting with eicosanoids, proinflammatory cytokines and nitric oxide as mediators. LÄS MER
4. Modeling glioblastoma heterogeneity to decipher its biology
Sammanfattning : Glioblastoma multiforme (GBM) is the most common and lethal form of primary brain tumor that mainly affects adults. GBM displays remarkable intra- and inter-tumoral heterogeneity and contains a subpopulation of cells named glioma stem cells that is believed to be responsible for tumor maintenance, progression and recurrence. LÄS MER
5. Role of MYCN in retinoblastoma : From carcinogenesis to tumor progression
Sammanfattning : Retinoblastoma, a pediatric malignancy of the retina, is primarily driven by the bi-allelic inactivation of the RB1gene. However, a subset of cases are characterized by proficient RB1 functions but with MYCN copy number mutations, suggesting an alternative oncogenic mechanism in the absence of RB1 mutations. LÄS MER