Sökning: "MAPKK"
Hittade 3 avhandlingar innehållade ordet MAPKK.
1. DNA checkpoint override and redox signaling in Schizosaccharomyces pombe
Sammanfattning : This thesis covers intracellular stress signaling through genotoxic stress, overriding of checkpoint control, as well as cellular redox status in hypoxic and oxidative stress Papers I and II: Caffeine has been shown to override cell cycle checkpoints in humans as well as in the fission yeast Schizosaccharomyces pombe. Understanding of the mechanism may aid in the development of compounds with similar overriding mechanisms for sensitization in cancer therapy. LÄS MER
2. Changes in mitogen-activated protein kinase phosphorylation and inorganic phosphate induced by skeletal muscle contraction
Sammanfattning : Skeletal muscles adjust to the level of contractile activity by different biochemical alterations. Contraction is a multifactorial stimulus with short-term metabolic effects and long-term responses due to changes in protein synthesis. LÄS MER
3. Adenosine receptor signaling and the activation of mitogen-activated protein kinases
Sammanfattning : The nucleoside adenosine is present in all cells and body fluids of all living organisms; its production, both intracellularly and extracellularly, is tightly coupled to energy consumption resulting in increasing extracellular adenosine levels with increased energy consumption. Adenosine is metabolized by adenosine deaminase and adenosine kinase. LÄS MER
